ID   F8WA42_HUMAN            Unreviewed;       358 AA.
AC   F8WA42;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 54.
DE   SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000341938};
GN   Name=SUMF2 {ECO:0000313|Ensembl:ENSP00000341938};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000341938, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000341938, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000341938}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC092101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8WA42; -.
DR   jPOST; F8WA42; -.
DR   MaxQB; F8WA42; -.
DR   PeptideAtlas; F8WA42; -.
DR   PRIDE; F8WA42; -.
DR   Ensembl; ENST00000342190; ENSP00000341938; ENSG00000129103.
DR   UCSC; uc003trv.4; human.
DR   EuPathDB; HostDB:ENSG00000129103.17; -.
DR   HGNC; HGNC:20415; SUMF2.
DR   OpenTargets; ENSG00000129103; -.
DR   eggNOG; ENOG410IFQ0; Eukaryota.
DR   eggNOG; COG1262; LUCA.
DR   GeneTree; ENSGT00390000008983; -.
DR   PhylomeDB; F8WA42; -.
DR   TreeFam; TF324027; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000129103; Expressed in 196 organ(s), highest expression level in right uterine tube.
DR   ExpressionAtlas; F8WA42; baseline and differential.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR005532; SUMF_dom.
DR   Pfam; PF03781; FGE-sulfatase; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:F8WA42,
KW   ECO:0000213|MaxQB:F8WA42, ECO:0000213|PeptideAtlas:F8WA42};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     44       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        45    358       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003385456.
FT   DOMAIN       46    246       FGE-sulfatase.
FT                                {ECO:0000259|Pfam:PF03781}.
SQ   SEQUENCE   358 AA;  39475 MW;  3E4ACD63A722D79C CRC64;
     MRAHAQRGRG CTRRSAAVLM ARHGLPLLPL LSLLVGAWLK LGNGQATSMV QLQGGRFLMG
     TNSPDSRDGD GPVREATVKP FAIDIFPVTN KDFRDFVREK KYRTEAEMFG WSFVFEDFVS
     DELRNKATQP MKSVLWWLPV EKAFWRQPAG PGSGIRERLE HPVLHVSWND ARAYCAWRGK
     RLPTEEEWEF AARGGLKGQV YPWGNWFQPN RTNLWQGKFP KGDKAEDGFH GVSPVNAFPA
     QNNYGWATLQ IQPQTTSVSA VLQTQAGRQG SCKQPGGDKE KSLLGSLSFP GHVANSAIPS
     SRASASGKNF PFPVSHPSVA GASHQGRRGL SLLCFGEGAQ CVLTMAGGQV FLLEAKYY
//