ID   F8W947_HUMAN            Unreviewed;        63 AA.
AC   F8W947;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 46.
DE   SubName: Full=Linker for activation of T-cells family member 2 {ECO:0000313|Ensembl:ENSP00000354374};
DE   Flags: Fragment;
GN   Name=LAT2 {ECO:0000313|Ensembl:ENSP00000354374};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000354374, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000354374, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000213|PubMed:19369195}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19369195; DOI=10.1074/mcp.M800588-MCP200;
RA   Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,
RA   Mann M., Daub H.;
RT   "Large-scale proteomics analysis of the human kinome.";
RL   Mol. Cell. Proteomics 8:1751-1764(2009).
RN   [3] {ECO:0000313|Ensembl:ENSP00000354374}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC005081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8W947; -.
DR   jPOST; F8W947; -.
DR   PeptideAtlas; F8W947; -.
DR   Ensembl; ENST00000361082; ENSP00000354374; ENSG00000086730.
DR   UCSC; uc064eiw.1; human.
DR   EuPathDB; HostDB:ENSG00000086730.16; -.
DR   HGNC; HGNC:12749; LAT2.
DR   OpenTargets; ENSG00000086730; -.
DR   eggNOG; ENOG410IZVX; Eukaryota.
DR   eggNOG; ENOG4111816; LUCA.
DR   GeneTree; ENSGT00390000006821; -.
DR   ChiTaRS; LAT2; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000086730; Expressed in 190 organ(s), highest expression level in blood.
DR   ExpressionAtlas; F8W947; baseline and differential.
DR   GO; GO:0042113; P:B cell activation; IEA:InterPro.
DR   GO; GO:0002764; P:immune response-regulating signaling pathway; IEA:InterPro.
DR   InterPro; IPR031428; LAT2.
DR   PANTHER; PTHR15646; PTHR15646; 1.
DR   Pfam; PF15703; LAT2; 1.
DR   ProDom; PD332876; PD332876; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:F8W947,
KW   ECO:0000213|MaxQB:F8W947, ECO:0000213|PeptideAtlas:F8W947};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24     63       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008414390.
FT   NON_TER      63     63       {ECO:0000313|Ensembl:ENSP00000354374}.
SQ   SEQUENCE   63 AA;  6859 MW;  0AFEC956C6D0BEFB CRC64;
     MSSGTELLWP GAALLVLLGV AASLCVRCSR PGAKRSEKIY QQRSLREDQQ SFTGSRTYSL
     VGQ
//