ID   F8W8J5_HUMAN            Unreviewed;       240 AA.
AC   F8W8J5;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 54.
DE   SubName: Full=V-set and transmembrane domain-containing protein 2A {ECO:0000313|Ensembl:ENSP00000384103};
GN   Name=VSTM2A {ECO:0000313|Ensembl:ENSP00000384103};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000384103, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000384103, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000384103}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC011228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC069313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001287938.1; NM_001301009.1.
DR   UniGene; Hs.335933; -.
DR   UniGene; Hs.731937; -.
DR   ProteinModelPortal; F8W8J5; -.
DR   PRIDE; F8W8J5; -.
DR   Ensembl; ENST00000402613; ENSP00000384103; ENSG00000170419.
DR   GeneID; 222008; -.
DR   UCSC; uc064dsa.1; human.
DR   CTD; 222008; -.
DR   EuPathDB; HostDB:ENSG00000170419.10; -.
DR   HGNC; HGNC:28499; VSTM2A.
DR   OpenTargets; ENSG00000170419; -.
DR   eggNOG; ENOG410IKN2; Eukaryota.
DR   eggNOG; ENOG410YG4F; LUCA.
DR   GeneTree; ENSGT00940000160556; -.
DR   OrthoDB; 1216208at2759; -.
DR   GenomeRNAi; 222008; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000170419; Expressed in 92 organ(s), highest expression level in primary visual cortex.
DR   ExpressionAtlas; F8W8J5; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:F8W8J5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    240       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379416.
FT   DOMAIN       27    143       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   240 AA;  26465 MW;  953964E8C4A0300D CRC64;
     MMGIFLVYVG FVFFSVLYVQ QGLSSQAKFT EFPRNVTATE GQNVEMSCAF QSGSASVYLE
     IQWWFLRGPE DLDPGAEGAG AQVELLPDRD PDSDGTKIST VKVQGNDISH KLQISKVRKK
     DEGLYECRVT DANYGELQEH KAQAYLKVNA NSHARRMQAF EASPMWLQDM KPRKNVSAAI
     PSSIHGSANQ RTHSTSSPQV VAKIPKQSPQ SAKSKSPVKS TERTAKLTLN SKHHPAPTVL
//