ID   F8W8D9_HUMAN            Unreviewed;       175 AA.
AC   F8W8D9;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000302544};
GN   Name=PAM {ECO:0000313|Ensembl:ENSP00000302544};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000302544, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000302544, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000302544}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC008501; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC008779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC010250; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC113373; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8W8D9; -.
DR   jPOST; F8W8D9; -.
DR   PeptideAtlas; F8W8D9; -.
DR   PRIDE; F8W8D9; -.
DR   Ensembl; ENST00000345721; ENSP00000302544; ENSG00000145730.
DR   UCSC; uc063fts.1; human.
DR   EuPathDB; HostDB:ENSG00000145730.20; -.
DR   HGNC; HGNC:8596; PAM.
DR   OpenTargets; ENSG00000145730; -.
DR   eggNOG; KOG3567; Eukaryota.
DR   eggNOG; ENOG410XS0X; LUCA.
DR   GeneTree; ENSGT00940000156369; -.
DR   ChiTaRS; PAM; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000145730; Expressed in 239 organ(s), highest expression level in endometrium.
DR   ExpressionAtlas; F8W8D9; baseline and differential.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F8W8D9,
KW   ECO:0000213|PeptideAtlas:F8W8D9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    175       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379500.
SQ   SEQUENCE   175 AA;  19649 MW;  4AE3C1A44A1FE936 CRC64;
     MAGRVPSLLV LLVFPSSCLA FRSPLSVFKR FKETTRPFSN ECLGTTRPVV PIDSSDFALD
     IRMPGVTPKQ LTSSLEPAWI LSITCYFLDA ICLHPLEVTG FVMKEPVQIK PIFCMPGREM
     LPLPGSPKVL DSELEERLEV NTLYYRYTMG ILVLLEIITR TVLVCPYTSH VCHSL
//