ID   F8W6G6_HUMAN            Unreviewed;       643 AA.
AC   F8W6G6;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   16-JAN-2019, entry version 48.
DE   SubName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 3 {ECO:0000313|Ensembl:ENSP00000345184};
GN   Name=LILRB3 {ECO:0000313|Ensembl:ENSP00000345184};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000345184, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000345184, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000345184}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC245052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F8W6G6; -.
DR   jPOST; F8W6G6; -.
DR   PRIDE; F8W6G6; -.
DR   Ensembl; ENST00000346401; ENSP00000345184; ENSG00000204577.
DR   UCSC; uc061cos.1; human.
DR   EuPathDB; HostDB:ENSG00000204577.11; -.
DR   HGNC; HGNC:6607; LILRB3.
DR   OpenTargets; ENSG00000204577; -.
DR   GeneTree; ENSGT00940000153160; -.
DR   OMA; CGSQEGY; -.
DR   ChiTaRS; LILRB3; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000204577; Expressed in 225 organ(s), highest expression level in blood.
DR   ExpressionAtlas; F8W6G6; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF13895; Ig_2; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    643       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003379631.
FT   TRANSMEM    456    477       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27     98       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   643 AA;  70571 MW;  04A76A6B5E05364B CRC64;
     MTPALTALLC LGLSLGPRTR MQAGPFPKPT LWAEPGSVIS WGSPVTIWCQ GSLEAQEYQL
     DKEGSPEPWD RNNPLEPKNK ARFSIPSMTQ HHAGRYRCHY YSSAGWSEPS DPLELVMTGF
     YNKPTLSALP SPVVASGGNM TLRCGSQKGY HHFVLMKEGE HQLPRTLDSQ QLHSGGFQAL
     FPVGPVTPSH RWRFTCYYYY TNTPWVWSHP SDPLEILPSG VSRKPSLLTL QGPVLAPGQS
     LTLQCGSDVG YDRFVLYKEG ERDFLQRPGQ QPQAGLSQAN FTLGPVSRSY GGQYRCYGAH
     NLSSEWSAPS DPLDILITGQ IYDTVSLSAQ PGPTVASGEN MTLLCQSRGY FDTFLLTKEG
     AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSR SSNPHLLSFP SEPLELMVSG
     PEDQPLNPPG SGPQNAPGLG SGAGTRAAGL GRYLEVLIGV SVAFVLLLFL LLFLLLLRQR
     HSKHRTSDQR KTDFQRPAGA AETEPKDRGL LRRSSPAADV QEENLYAAVK DTQSEDRVEL
     DSQSPHDEDP QAVTYAPVKH SSPRREMASP PSSLSGEFLD TKDRQVEEDR QMDTEAAASE
     ASQDVTYAQL HSLTLRRKAT EPPPSQEGEP PAEPSIYATL AIH
//