ID   F6UB75_HUMAN            Unreviewed;       175 AA.
AC   F6UB75;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   13-FEB-2019, entry version 43.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000412457};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000412457, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000412457, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000412457}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL645941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F6UB75; -.
DR   SMR; F6UB75; -.
DR   BioMuta; ENSG00000248993; -.
DR   jPOST; F6UB75; -.
DR   PRIDE; F6UB75; -.
DR   Ensembl; ENST00000429234; ENSP00000412457; ENSG00000248993.
DR   UCSC; uc063nso.1; human.
DR   EuPathDB; HostDB:ENSG00000248993.1; -.
DR   GeneCards; ENSG00000248993; -.
DR   eggNOG; ENOG410YU9X; LUCA.
DR   GeneTree; ENSGT00940000160381; -.
DR   InParanoid; F6UB75; -.
DR   OMA; NCASHTK; -.
DR   PhylomeDB; F6UB75; -.
DR   TreeFam; TF335727; -.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000248993; Expressed in 60 organ(s), highest expression level in adult mammalian kidney.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   Gene3D; 3.10.320.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF54452; SSF54452; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    175       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003347744.
FT   DOMAIN       59    137       MHC_II_beta. {ECO:0000259|SMART:SM00921}.
FT   NON_TER     175    175       {ECO:0000313|Ensembl:ENSP00000412457}.
SQ   SEQUENCE   175 AA;  19438 MW;  7C8B3677DE7E6717 CRC64;
     MGHEQNQGAA LLQMLPLLWL LPHSWAVPEE QSMITFLPLL LGLSLGCTGA GGFVAHVEST
     CLLDDAGTPK DFTYCISFNK DLLTCWDPEE NKMAPCEFGV LNSLANVLSQ HLNQKDTLMQ
     RLRNGLQNCA THTQPFWGSL TNRTRPPSVQ VAKTTPFNTR EPVMLACYVW GFYPA
//