ID   F5H5Y1_HUMAN            Unreviewed;       350 AA.
AC   F5H5Y1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   12-SEP-2018, entry version 42.
DE   SubName: Full=Solute carrier family 52, riboflavin transporter, member 1 {ECO:0000313|Ensembl:ENSP00000443026};
GN   Name=SLC52A1 {ECO:0000313|Ensembl:ENSP00000443026};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000443026, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000443026, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000443026}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC012146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5H5Y1; -.
DR   PeptideAtlas; F5H5Y1; -.
DR   Ensembl; ENST00000512825; ENSP00000443026; ENSG00000132517.
DR   UCSC; uc010ckx.4; human.
DR   EuPathDB; HostDB:ENSG00000132517.14; -.
DR   HGNC; HGNC:30225; SLC52A1.
DR   OpenTargets; ENSG00000132517; -.
DR   eggNOG; KOG4255; Eukaryota.
DR   eggNOG; ENOG410YE1U; LUCA.
DR   GeneTree; ENSGT00390000003774; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000132517; Expressed in 66 organ(s), highest expression level in placenta.
DR   ExpressionAtlas; F5H5Y1; baseline and differential.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0032217; F:riboflavin transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR009357; Riboflavin_transptr.
DR   PANTHER; PTHR12929; PTHR12929; 1.
DR   Pfam; PF06237; DUF1011; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    350       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003323098.
FT   TRANSMEM     49     68       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     80    100       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    112    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    168       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    196    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    311    335       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   350 AA;  36535 MW;  828BF8B9859403B8 CRC64;
     MAAPTLGRLV LTHLLVALFG MGSWAAVNGI WVELPVVVKD LPEGWSLPSY LSVVVALGNL
     GLLVVTLWRQ LAPGKGEQVP IQVVQVLSVV GTALLAPLWH HVAPVAGQLH SVAFLTLALV
     LAMACCTSNV TFLPFLSHLP PPFLRSFFLG QGLSALLPCV LALVQGVGRL ECPPAPTNGT
     SGPPLDFPER FPASTFFWAL TALLVTSAAA FRGLLLLLPS LPSVTTGGSG PELQLGSPGA
     EEEEKEEEEA LPLQEPPSQA AGTIPGPDPE AHQLFSAHGA FLLGLMAFTS AVTNGVLPSV
     QSFSCLPYGR LAYHLAVVLG SAANPLACFL AMGVLCRCCR GCCVCVCSHM
//