ID   F5H4Z6_HUMAN            Unreviewed;       171 AA.
AC   F5H4Z6;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000444794};
DE   Flags: Fragment;
GN   Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000444794};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000444794, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000444794, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000444794}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5H4Z6; -.
DR   jPOST; F5H4Z6; -.
DR   PeptideAtlas; F5H4Z6; -.
DR   PRIDE; F5H4Z6; -.
DR   Ensembl; ENST00000535625; ENSP00000444794; ENSG00000165457.
DR   UCSC; uc058fae.1; human.
DR   EuPathDB; HostDB:ENSG00000165457.13; -.
DR   HGNC; HGNC:3793; FOLR2.
DR   OpenTargets; ENSG00000165457; -.
DR   eggNOG; ENOG410IFFP; Eukaryota.
DR   eggNOG; ENOG4111IU4; LUCA.
DR   GeneTree; ENSGT00940000153758; -.
DR   ChiTaRS; FOLR2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000165457; Expressed in 215 organ(s), highest expression level in esophagus.
DR   ExpressionAtlas; F5H4Z6; baseline and differential.
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0061714; F:folic acid receptor activity; IEA:InterPro.
DR   GO; GO:1904447; P:folate import across plasma membrane; IEA:InterPro.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR032937; FOLR2.
DR   PANTHER; PTHR10517; PTHR10517; 1.
DR   PANTHER; PTHR10517:SF8; PTHR10517:SF8; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F5H4Z6,
KW   ECO:0000213|PeptideAtlas:F5H4Z6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    171       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003327594.
FT   DOMAIN       30    171       Folate_rec. {ECO:0000259|Pfam:PF03024}.
FT   NON_TER     171    171       {ECO:0000313|Ensembl:ENSP00000444794}.
SQ   SEQUENCE   171 AA;  20027 MW;  F4BE9529287F62E0 CRC64;
     MVWKWMPLLL LLVCVATMCS AQDRTDLLNV CMDAKHHKTK PGPEDKLHDQ CSPWKKNACC
     TASTSQELHK DTSRLYNFNW DHCGKMEPAC KRHFIQDTCL YECSPNLGPW IQQVNQSWRK
     ERFLDVPLCK EDCQRWWEDC HTSHTCKSNW HRGWDWTSGV NKCPAGALCR T
//