ID   F5H3Z7_HUMAN            Unreviewed;       106 AA.
AC   F5H3Z7;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000438559};
GN   Name=PDE2A {ECO:0000313|Ensembl:ENSP00000438559};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000438559, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000438559, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000438559}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP003065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP005019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; F5H3Z7; -.
DR   MaxQB; F5H3Z7; -.
DR   PeptideAtlas; F5H3Z7; -.
DR   PRIDE; F5H3Z7; -.
DR   Ensembl; ENST00000536308; ENSP00000438559; ENSG00000186642.
DR   UCSC; uc058fbt.1; human.
DR   EuPathDB; HostDB:ENSG00000186642.15; -.
DR   HGNC; HGNC:8777; PDE2A.
DR   OpenTargets; ENSG00000186642; -.
DR   eggNOG; KOG3689; Eukaryota.
DR   eggNOG; ENOG410XRI7; LUCA.
DR   GeneTree; ENSGT00940000159817; -.
DR   ChiTaRS; PDE2A; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000186642; Expressed in 183 organ(s), highest expression level in right frontal lobe.
DR   ExpressionAtlas; F5H3Z7; baseline and differential.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:F5H3Z7,
KW   ECO:0000213|MaxQB:F5H3Z7, ECO:0000213|PeptideAtlas:F5H3Z7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    106       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003323060.
SQ   SEQUENCE   106 AA;  11591 MW;  44943D79F82ECCD1 CRC64;
     MVLVLHHILI AVVQFLRRGQ QVFLKPDEPP PPPQPCADSL QDALLSLGSV IDISGLQRAV
     KEALSAVLPR VETVYTYLLD GESQLVCEDP PHELPQEGKV RCTVAS
//