ID   F5H3Z4_HUMAN            Unreviewed;       198 AA.
AC   F5H3Z4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000438568};
DE   Flags: Fragment;
GN   Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000438568};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000438568, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000438568, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000438568}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5H3Z4; -.
DR   SMR; F5H3Z4; -.
DR   jPOST; F5H3Z4; -.
DR   PeptideAtlas; F5H3Z4; -.
DR   PRIDE; F5H3Z4; -.
DR   Ensembl; ENST00000536778; ENSP00000438568; ENSG00000165457.
DR   UCSC; uc058fad.1; human.
DR   EuPathDB; HostDB:ENSG00000165457.13; -.
DR   HGNC; HGNC:3793; FOLR2.
DR   OpenTargets; ENSG00000165457; -.
DR   eggNOG; ENOG410IFFP; Eukaryota.
DR   eggNOG; ENOG4111IU4; LUCA.
DR   GeneTree; ENSGT00940000153758; -.
DR   ChiTaRS; FOLR2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000165457; Expressed in 215 organ(s), highest expression level in esophagus.
DR   ExpressionAtlas; F5H3Z4; baseline and differential.
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0061714; F:folic acid receptor activity; IEA:InterPro.
DR   GO; GO:1904447; P:folate import across plasma membrane; IEA:InterPro.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR032937; FOLR2.
DR   PANTHER; PTHR10517; PTHR10517; 1.
DR   PANTHER; PTHR10517:SF8; PTHR10517:SF8; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F5H3Z4,
KW   ECO:0000213|PeptideAtlas:F5H3Z4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     36       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        37    198       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003327255.
FT   DOMAIN       45    198       Folate_rec. {ECO:0000259|Pfam:PF03024}.
FT   NON_TER     198    198       {ECO:0000313|Ensembl:ENSP00000438568}.
SQ   SEQUENCE   198 AA;  23007 MW;  70A485C667C3B559 CRC64;
     MLPAATELRL QGQKDMVWKW MPLLLLLVCV ATMCSAQDRT DLLNVCMDAK HHKTKPGPED
     KLHDQCSPWK KNACCTASTS QELHKDTSRL YNFNWDHCGK MEPACKRHFI QDTCLYECSP
     NLGPWIQQVN QSWRKERFLD VPLCKEDCQR WWEDCHTSHT CKSNWHRGWD WTSGVNKCPA
     GALCRTFESY FPTPAALC
//