ID   F5H2L1_HUMAN            Unreviewed;       241 AA.
AC   F5H2L1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   13-FEB-2019, entry version 58.
DE   SubName: Full=Adhesion G-protein-coupled receptor G6 {ECO:0000313|Ensembl:ENSP00000446287};
DE   Flags: Fragment;
GN   Name=ADGRG6 {ECO:0000313|Ensembl:ENSP00000446287};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000446287, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000446287, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000446287}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR   EMBL; AL033377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL360007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5H2L1; -.
DR   SMR; F5H2L1; -.
DR   MaxQB; F5H2L1; -.
DR   PeptideAtlas; F5H2L1; -.
DR   PRIDE; F5H2L1; -.
DR   Ensembl; ENST00000541199; ENSP00000446287; ENSG00000112414.
DR   UCSC; uc063rxz.1; human.
DR   EuPathDB; HostDB:ENSG00000112414.14; -.
DR   HGNC; HGNC:13841; ADGRG6.
DR   OpenTargets; ENSG00000112414; -.
DR   eggNOG; KOG3714; Eukaryota.
DR   eggNOG; KOG4193; Eukaryota.
DR   eggNOG; ENOG410XSD2; LUCA.
DR   GeneTree; ENSGT00940000155621; -.
DR   ChiTaRS; ADGRG6; human.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000112414; Expressed in 179 organ(s), highest expression level in lung.
DR   ExpressionAtlas; F5H2L1; baseline and differential.
DR   CDD; cd00041; CUB; 1.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR001759; Pentraxin-related.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   Pfam; PF00431; CUB; 1.
DR   SMART; SM00042; CUB; 1.
DR   SUPFAM; SSF49854; SSF49854; 1.
DR   PROSITE; PS01180; CUB; 1.
DR   PROSITE; PS51828; PTX_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00059,
KW   ECO:0000256|SAAS:SAAS01008102};
KW   Proteomics identification {ECO:0000213|MaxQB:F5H2L1,
KW   ECO:0000213|PeptideAtlas:F5H2L1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     36       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        37    241       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003324731.
FT   DOMAIN       40    148       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DISULFID     93    110       {ECO:0000256|PROSITE-ProRule:PRU00059}.
FT   NON_TER     241    241       {ECO:0000313|Ensembl:ENSP00000446287}.
SQ   SEQUENCE   241 AA;  26882 MW;  B20D53AAF0D95189 CRC64;
     MFRSDRMWSC HWKWKPSPLL FLFALYIMCV PHSVWGCANC RVVLSNPSGT FTSPCYPNDY
     PNSQACMWTL RAPTGYIIQI TFNDFDIEEA PNCIYDSLSL DNGESQTKFC GATAKGLSFN
     SSANEMHVSF SSDFSIQKKG FNASYIRVAV SLRNQKVILP QTSDAYQVSV AKSISIPELS
     AFTLCFEATK VGHEDSDWTA FSYSNASFTQ LLSFGKAKSG YFLSISDSKC LLNNALPVKE
     K
//