ID   F5GZ20_HUMAN            Unreviewed;       158 AA.
AC   F5GZ20;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   05-DEC-2018, entry version 41.
DE   SubName: Full=Potassium channel subfamily K member 4 {ECO:0000313|Ensembl:ENSP00000441460};
GN   Name=KCNK4 {ECO:0000313|Ensembl:ENSP00000441460};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000441460, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000441460, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000441460}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP001453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5GZ20; -.
DR   Ensembl; ENST00000541349; ENSP00000441460; ENSG00000182450.
DR   UCSC; uc058cwq.1; human.
DR   EuPathDB; HostDB:ENSG00000182450.12; -.
DR   HGNC; HGNC:6279; KCNK4.
DR   OpenTargets; ENSG00000182450; -.
DR   eggNOG; KOG1418; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00940000160310; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000182450; Expressed in 38 organ(s), highest expression level in amygdala.
DR   ExpressionAtlas; F5GZ20; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   InterPro; IPR003976; 2pore_dom_K_chnl_TREK.
DR   InterPro; IPR013099; K_chnl_dom.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   PRINTS; PR01499; TREKCHANNEL.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    158       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003327538.
FT   TRANSMEM     90    111       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    118    138       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       86    142       Ion_trans_2. {ECO:0000259|Pfam:PF07885}.
SQ   SEQUENCE   158 AA;  16911 MW;  1D0821E3A9CCCB04 CRC64;
     MRSTTLLALL ALVLLYLVSG ALVFRALEQP HEQQAQRELG EVREKFLRAH PCVSDQELGL
     LIKEVADALG GGADPETNST SNSSHSAWDL GSAFFFSGTI ITTIGYGNVA LRTDAGRLFC
     IFYALVGIPL FGILLAGVGD RLGSSLRHGI GHIEAIFL
//