ID   F5GY04_HUMAN            Unreviewed;       987 AA.
AC   F5GY04;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   16-JAN-2019, entry version 61.
DE   SubName: Full=Zinc finger protein basonuclin-1 {ECO:0000313|Ensembl:ENSP00000456727};
GN   Name=BNC1 {ECO:0000313|Ensembl:ENSP00000456727};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000456727, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000456727, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000456727}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC103876; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001288135.1; NM_001301206.1.
DR   UniGene; Hs.459153; -.
DR   ProteinModelPortal; F5GY04; -.
DR   EPD; F5GY04; -.
DR   MaxQB; F5GY04; -.
DR   PRIDE; F5GY04; -.
DR   Ensembl; ENST00000569704; ENSP00000456727; ENSG00000169594.
DR   GeneID; 646; -.
DR   UCSC; uc059mqn.1; human.
DR   CTD; 646; -.
DR   EuPathDB; HostDB:ENSG00000169594.12; -.
DR   HGNC; HGNC:1081; BNC1.
DR   OpenTargets; ENSG00000169594; -.
DR   eggNOG; ENOG410IE3V; Eukaryota.
DR   eggNOG; ENOG410YN2D; LUCA.
DR   GeneTree; ENSGT00390000005844; -.
DR   OrthoDB; 96985at2759; -.
DR   GenomeRNAi; 646; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000169594; Expressed in 75 organ(s), highest expression level in germinal epithelium of ovary.
DR   ExpressionAtlas; F5GY04; baseline and differential.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR040436; Disconnected-like.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR15021; PTHR15021; 1.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Proteomics identification {ECO:0000213|EPD:F5GY04,
KW   ECO:0000213|PeptideAtlas:F5GY04};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    987       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003322980.
FT   DOMAIN      350    378       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      713    741       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      921    944       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
SQ   SEQUENCE   987 AA;  109830 MW;  35C50E8B9A4844BD CRC64;
     MRCRNMFFSF KASLCGCGAA TAPSLTAISC TLNCSCQSFK PGKINHRQCD QCKHGWVAHA
     LSKLRIPPMY PTSQVEIVQS NVVFDISSLM LYGTQAIPVR LKILLDRLFS VLKQDEVLQI
     LHALDWTLQD YIRGYVLQDA SGKVLDHWSI MTSEEEVATL QQFLRFGETK SIVELMAIQE
     KEEQSIIIPP STANVDIRAF IESCSHRSSS LPTPVDKGNP SSIHPFENLI SNMTFMLPFQ
     FFNPLPPALI GSLPEQYMLE QGHDQSQDPK QEVHGPFPDS SFLTSSSTPF QVEKDQCLNC
     PDAITKKEDS THLSDSSSYN IVTKFERTQL SPEAKVKPER NSLGTKKGRV FCTACEKTFY
     DKGTLKIHYN AVHLKIKHKC TIEGCNMVFS SLRSRNRHSA NPNPRLHMPM NRNNRDKDLR
     NSLNLASSEN YKCPGFTVTS PDCRPPPSYP GSGEDSKGQP AFPNIGQNGV LFPNLKTVQP
     VLPFYRSPAT PAEVANTPGI LPSLPLLSSS IPEQLISNEM PFDALPKKKS RKSSMPIKIE
     KEAVEIANEK RHNLSSDEDM PLQVVSEDEQ EACSPQSHRV SEEQHVQSGG LGKPFPEGER
     PCHRESVIES SGAISQTPEQ ATHNSERETE QTPALIMVPR EVEDGGHEHY FTPGMEPQVP
     FSDYMELQQR LLAGGLFSAL SNRGMAFPCL EDSKELEHVG QHALARQIEE NRFQCDICKK
     TFKNACSVKI HHKNMHVKEM HTCTVEGCNA TFPSRRSRDR HSSNLNLHQK ALSQEALESS
     EDHFRAAYLL KDVAKEAYQD VAFTQQASQT SVIFKGTSRM GSLVYPITQV HSASLESYNS
     GPLSEGTILD LSTTSSMKSE SSSHSSWDSD GVSEEGTVLM EDSDGNCEGS SLVPGEDEYP
     ICVLMEKADQ SLASLPSGLP ITCHLCQKTY SNKGTFRAHY KTVHLRQLHK CKVPGCNTMF
     SSVRSRNRHS QNPNLHKSLA SSPSHLQ
//