ID   F2Z3N3_HUMAN            Unreviewed;       751 AA.
AC   F2Z3N3;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Olfactomedin-like protein 2B {ECO:0000313|Ensembl:ENSP00000356917};
GN   Name=OLFML2B {ECO:0000313|Ensembl:ENSP00000356917};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000356917, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000356917, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000356917}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00446}.
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DR   EMBL; AL391825; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL590408; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001284642.1; NM_001297713.1.
DR   UniGene; Hs.507515; -.
DR   ProteinModelPortal; F2Z3N3; -.
DR   MaxQB; F2Z3N3; -.
DR   PeptideAtlas; F2Z3N3; -.
DR   PRIDE; F2Z3N3; -.
DR   Ensembl; ENST00000367940; ENSP00000356917; ENSG00000162745.
DR   GeneID; 25903; -.
DR   UCSC; uc010pkq.3; human.
DR   CTD; 25903; -.
DR   EuPathDB; HostDB:ENSG00000162745.10; -.
DR   HGNC; HGNC:24558; OLFML2B.
DR   OpenTargets; ENSG00000162745; -.
DR   eggNOG; KOG3545; Eukaryota.
DR   eggNOG; ENOG410ZJ72; LUCA.
DR   GeneTree; ENSGT00940000157757; -.
DR   OMA; QKETTWR; -.
DR   OrthoDB; 311650at2759; -.
DR   PhylomeDB; F2Z3N3; -.
DR   ChiTaRS; OLFML2B; human.
DR   GenomeRNAi; 25903; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000162745; Expressed in 194 organ(s), highest expression level in connective tissue.
DR   ExpressionAtlas; F2Z3N3; baseline and differential.
DR   GO; GO:0031012; C:extracellular matrix; IEA:Ensembl.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   InterPro; IPR003112; Olfac-like_dom.
DR   InterPro; IPR031233; OLFML2B.
DR   PANTHER; PTHR23192:SF37; PTHR23192:SF37; 1.
DR   Pfam; PF02191; OLF; 1.
DR   SMART; SM00284; OLF; 1.
DR   PROSITE; PS51132; OLF; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F2Z3N3,
KW   ECO:0000213|PeptideAtlas:F2Z3N3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    751       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003290161.
FT   DOMAIN      494    751       Olfactomedin-like.
FT                                {ECO:0000259|PROSITE:PS51132}.
FT   COILED      181    212       {ECO:0000256|SAM:Coils}.
FT   COILED      300    320       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   751 AA;  84127 MW;  F8F8E8B6FFF73499 CRC64;
     MAKPRLLVLY FALIVVPAWV SSIVLTGTSE PPDAQTVAPA EDETLQNEAD NQENVLSQLL
     GDYDKVKAMS EGSDCQCKCV VRPLGRDACQ RINAGASRKE DFYTVETITS GSSCKCACVA
     PPSALNPCEG DFRLQKLREA DSQDLKLSTI IDMLEGAFYG LDLLKLHSVT TKLVGRVDKL
     EEEVSKNLTK ENEQIKEDME EIRTEMNKRG KENCSENILD SMPDIRSALQ RDAAAAYAHP
     EQYEERFLQE ETVSQQINSI ELLQTRPLAL PEVVKSQRPL QRQVHLRGRP ASQPTVIRGI
     TYYKAKVSEE ENDIEEQQDE FFSGDNGVDL LIEDQLLRHN GLMTSVTRRP AATRQGHSTA
     VTSDLNARTA PWSSALPQPS TSDPSIANHA SVGPTLQTTS VSPDPTRESV LQPSPQVPAT
     TVAHTATQQP AAPAPPAVSP REALMEAMHT VPVPPTTVRT DSLGKDAPAG WGTTPASPTL
     SPEEEDDIRN VIGRCKDTLS TITGPTTQNT YGRNEGAWMK DPLAKDERIY VTNYYYGNTL
     VEFRNLENFK QGRWSNSYKL PYSWIGTGHV VYNGAFYYNR AFTRNIIKYD LKQRYVAAWA
     MLHDVAYEEA TPWRWQGHSD VDFAVDENGL WLIYPALDDE GFSQEVIVLS KLNAADLSTQ
     KETTWRTGLR RNFYGNCFVI CGVLYAVDSY NQRNANISYA FDTHTNTQIV PRLLFENEYS
     YTTQIDYNPK DRLLYAWDNG HQVTYHVIFA Y
//