ID   F2Z2C8_HUMAN            Unreviewed;       236 AA.
AC   F2Z2C8;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   16-JAN-2019, entry version 55.
DE   SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 {ECO:0000313|Ensembl:ENSP00000436263};
GN   Name=ST6GALNAC5 {ECO:0000313|Ensembl:ENSP00000436263};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436263, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000436263, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000436263}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC       {ECO:0000256|SAAS:SAAS01027238}.
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DR   EMBL; AC096951; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC099060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL035409; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL954680; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BX284687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F2Z2C8; -.
DR   SMR; F2Z2C8; -.
DR   jPOST; F2Z2C8; -.
DR   PeptideAtlas; F2Z2C8; -.
DR   PRIDE; F2Z2C8; -.
DR   Ensembl; ENST00000318803; ENSP00000436263; ENSG00000117069.
DR   UCSC; uc009wbw.4; human.
DR   EuPathDB; HostDB:ENSG00000117069.14; -.
DR   HGNC; HGNC:19342; ST6GALNAC5.
DR   OpenTargets; ENSG00000117069; -.
DR   eggNOG; KOG2692; Eukaryota.
DR   eggNOG; ENOG410XT8P; LUCA.
DR   GeneTree; ENSGT00940000157634; -.
DR   ChiTaRS; ST6GALNAC5; human.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000117069; Expressed in 129 organ(s), highest expression level in Ammon's horn.
DR   ExpressionAtlas; F2Z2C8; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008373; F:sialyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   Gene3D; 3.90.1480.20; -; 1.
DR   InterPro; IPR001675; Glyco_trans_29.
DR   InterPro; IPR038578; GT29-like_sf.
DR   Pfam; PF00777; Glyco_transf_29; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Glycosyltransferase {ECO:0000256|SAAS:SAAS01027230};
KW   Golgi apparatus {ECO:0000256|SAAS:SAAS01027226};
KW   Membrane {ECO:0000256|SAAS:SAAS01027233};
KW   Proteomics identification {ECO:0000213|MaxQB:F2Z2C8,
KW   ECO:0000213|PeptideAtlas:F2Z2C8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|SAAS:SAAS01027230};
KW   Transmembrane {ECO:0000256|SAAS:SAAS01027233};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS01027233}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    236       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003290981.
SQ   SEQUENCE   236 AA;  26261 MW;  A95163902953D5EE CRC64;
     MKTLMRHGLA VCLALTTMCT SLLLVYSSLG GQKERPPQQQ QQQQQQQQQA SATGSSQPAA
     ESSTQQRPGV PAGPRPLDGY LGVADHKPLK MHCRDCALVT SSGHLLHSRQ GSQIDQTECV
     IRMNDAPTRG YGRDVGNRTS LRVIAHSSIQ RILRNRHDLL NVSQGTVFIF WGPSSYMRRD
     GKGQVYNNLH LLSQVLPRLK AFMITRHKML QFDELFKQET GKDRYPTLGS ALAGLQ
//