ID   E9PR26_HUMAN            Unreviewed;       383 AA.
AC   E9PR26;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 47.
DE   SubName: Full=Junctional adhesion molecule-like {ECO:0000313|Ensembl:ENSP00000436117};
GN   Name=JAML {ECO:0000313|Ensembl:ENSP00000436117};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436117, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000436117, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000436117}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP002800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PR26; -.
DR   PeptideAtlas; E9PR26; -.
DR   PRIDE; E9PR26; -.
DR   Ensembl; ENST00000533261; ENSP00000436117; ENSG00000160593.
DR   UCSC; uc058hwp.1; human.
DR   EuPathDB; HostDB:ENSG00000160593.17; -.
DR   HGNC; HGNC:19084; JAML.
DR   OpenTargets; ENSG00000160593; -.
DR   eggNOG; ENOG410IKEA; Eukaryota.
DR   eggNOG; ENOG4111DWB; LUCA.
DR   GeneTree; ENSGT00900000141020; -.
DR   ChiTaRS; JAML; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000160593; Expressed in 170 organ(s), highest expression level in blood.
DR   ExpressionAtlas; E9PR26; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046629; P:gamma-delta T cell activation; IEA:InterPro.
DR   GO; GO:0050900; P:leukocyte migration; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR029871; JAML.
DR   InterPro; IPR000920; Myelin_P0-rel.
DR   PANTHER; PTHR13869; PTHR13869; 1.
DR   PANTHER; PTHR13869:SF22; PTHR13869:SF22; 1.
DR   Pfam; PF07686; V-set; 2.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PR26,
KW   ECO:0000213|PeptideAtlas:E9PR26};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    383       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244185.
FT   TRANSMEM    264    285       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       11    132       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   383 AA;  43009 MW;  3D1C8373D4CF2D17 CRC64;
     MFCPLKLILL PVLLDYSLGL NDLNVSPPEL TVHVGDSALM GCVFQSTEDK CIFKIDWTLS
     PGEHAKDEYV LYYYSNLSVP IGRFQNRVHL MGDILCNDGS LLLQDVQEAD QGTYICEIRL
     KGESQVFKKA VVLHVLPEEP KELMVHVGGL IQMGCVFQST EVKHVTKEEI VFRYYHKLRM
     SVEYSQSWGH FQNRVNLVGD IFRNDGSIML QGVRESDGGN YTCSIHLGNL VFKKTIVLHV
     SPEEPRTLVT PAALRPLVLG GNQLVIIVGI VCATILLLPV LILIVKKTCG NKSSVNSTVL
     VKNTKKTNPE IKEKPCHFER CEGEKHIYSP IIVREVIEEE EPSEKSEATY MTMHPVWPSL
     RSDRNNSLEK KSGGGMPKTQ QAF
//