ID   E9PR14_HUMAN            Unreviewed;        80 AA.
AC   E9PR14;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   RecName: Full=Serum amyloid A protein {ECO:0000256|RuleBase:RU000539};
GN   Name=SAA2 {ECO:0000313|Ensembl:ENSP00000432370};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000432370, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000432370, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000432370}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- FUNCTION: Major acute phase reactant. Apolipoprotein of the HDL
CC       complex. {ECO:0000256|RuleBase:RU000539}.
CC   -!- SIMILARITY: Belongs to the SAA family.
CC       {ECO:0000256|RuleBase:RU000539}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC090099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PR14; -.
DR   jPOST; E9PR14; -.
DR   PeptideAtlas; E9PR14; -.
DR   PRIDE; E9PR14; -.
DR   Ensembl; ENST00000530400; ENSP00000432370; ENSG00000134339.
DR   UCSC; uc057zpp.1; human.
DR   EuPathDB; HostDB:ENSG00000134339.8; -.
DR   HGNC; HGNC:10514; SAA2.
DR   OpenTargets; ENSG00000134339; -.
DR   eggNOG; ENOG410IXU4; Eukaryota.
DR   eggNOG; ENOG410YSBK; LUCA.
DR   GeneTree; ENSGT00390000004737; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000134339; Expressed in 84 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; E9PR14; baseline and differential.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-UniRule.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-UniRule.
DR   InterPro; IPR000096; Serum_amyloid_A.
DR   Pfam; PF00277; SAA; 1.
DR   PRINTS; PR00306; SERUMAMYLOID.
DR   SMART; SM00197; SAA; 1.
DR   PROSITE; PS00992; SAA; 1.
PE   3: Inferred from homology;
KW   Acute phase {ECO:0000256|RuleBase:RU000539};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   HDL {ECO:0000256|RuleBase:RU000539};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19     80       Serum amyloid A protein.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242918.
SQ   SEQUENCE   80 AA;  8952 MW;  5A335219DFFD2F19 CRC64;
     MKLLTGLVFC SLVLSVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY
     DAAKRGPGGA WAAEVIREDD
//