ID   E9PQZ2_HUMAN            Unreviewed;       209 AA.
AC   E9PQZ2;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 52.
DE   SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000432424};
DE   Flags: Fragment;
GN   Name=ST3GAL4 {ECO:0000313|Ensembl:ENSP00000432424};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000432424, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000432424, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000432424}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC       {ECO:0000256|SAAS:SAAS01027238}.
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DR   EMBL; AP000806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP001318; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PQZ2; -.
DR   SMR; E9PQZ2; -.
DR   jPOST; E9PQZ2; -.
DR   MaxQB; E9PQZ2; -.
DR   PeptideAtlas; E9PQZ2; -.
DR   PRIDE; E9PQZ2; -.
DR   Ensembl; ENST00000528858; ENSP00000432424; ENSG00000110080.
DR   UCSC; uc058izk.1; human.
DR   EuPathDB; HostDB:ENSG00000110080.18; -.
DR   HGNC; HGNC:10864; ST3GAL4.
DR   OpenTargets; ENSG00000110080; -.
DR   eggNOG; KOG2692; Eukaryota.
DR   eggNOG; ENOG410XT8P; LUCA.
DR   GeneTree; ENSGT00940000158893; -.
DR   ChiTaRS; ST3GAL4; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000110080; Expressed in 209 organ(s), highest expression level in left adrenal gland.
DR   ExpressionAtlas; E9PQZ2; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008373; F:sialyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   Gene3D; 3.90.1480.20; -; 1.
DR   InterPro; IPR001675; Glyco_trans_29.
DR   InterPro; IPR038578; GT29-like_sf.
DR   Pfam; PF00777; Glyco_transf_29; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Glycosyltransferase {ECO:0000256|SAAS:SAAS01027230};
KW   Golgi apparatus {ECO:0000256|SAAS:SAAS01027226};
KW   Membrane {ECO:0000256|SAAS:SAAS01027233};
KW   Proteomics identification {ECO:0000213|EPD:E9PQZ2,
KW   ECO:0000213|MaxQB:E9PQZ2, ECO:0000213|PeptideAtlas:E9PQZ2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|SAAS:SAAS01027230};
KW   Transmembrane {ECO:0000256|SAAS:SAAS01027233};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS01027233}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    209       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245453.
FT   NON_TER     209    209       {ECO:0000313|Ensembl:ENSP00000432424}.
SQ   SEQUENCE   209 AA;  23974 MW;  ECD8613EB3A9F358 CRC64;
     MVSKSRWKLL AMLALVLVVM VWYSISREDR YIELFYFPIP EKKEPCLQGE AESKASKLFG
     NYSRDQPIFL RLEDYFWVKT PSAYELPYGT KGSEDLLLRV LAITSSSIPK NIQSLRCRRC
     VVVGNGHRLR NSSLGDAINK YDVVIRLNNA PVAGYEGDVG SKTTMRLFYP ESAHFDPKVE
     NNPDTLLVLV AFKAMDFHWI ETILSDKKR
//