ID   E9PQW9_HUMAN            Unreviewed;       160 AA.
AC   E9PQW9;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000432466};
GN   Name=ACP2 {ECO:0000313|Ensembl:ENSP00000432466};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000432466, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000432466, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000432466}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000256|SAAS:SAAS00793915}.
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DR   EMBL; AC018410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PQW9; -.
DR   jPOST; E9PQW9; -.
DR   MaxQB; E9PQW9; -.
DR   PeptideAtlas; E9PQW9; -.
DR   PRIDE; E9PQW9; -.
DR   Ensembl; ENST00000531547; ENSP00000432466; ENSG00000134575.
DR   UCSC; uc058bcb.1; human.
DR   EuPathDB; HostDB:ENSG00000134575.9; -.
DR   HGNC; HGNC:123; ACP2.
DR   OpenTargets; ENSG00000134575; -.
DR   eggNOG; KOG3720; Eukaryota.
DR   eggNOG; ENOG410ZVBQ; LUCA.
DR   GeneTree; ENSGT00940000158446; -.
DR   ChiTaRS; ACP2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000134575; Expressed in 218 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; E9PQW9; baseline and differential.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; -; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; SSF53254; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:E9PQW9,
KW   ECO:0000213|MaxQB:E9PQW9, ECO:0000213|PeptideAtlas:E9PQW9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    160       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244181.
SQ   SEQUENCE   160 AA;  18536 MW;  442F88EAC16391D7 CRC64;
     MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLLY RHGDRSPVKT YPKDPYQEEE
     WPQGFGQLTK EGMLQHWELG QALRQRYHGF LNTSYHRQEV YVRSTDFDRT LMSAEANLAG
     LFPPNGMQRF NPNISWQPIP VHTVPITEDR SRTETLIHFS
//