ID   E9PQS8_HUMAN            Unreviewed;        93 AA.
AC   E9PQS8;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   12-SEP-2018, entry version 47.
DE   SubName: Full=Sodium channel subunit beta-3 {ECO:0000313|Ensembl:ENSP00000434363};
DE   Flags: Fragment;
GN   Name=SCN3B {ECO:0000313|Ensembl:ENSP00000434363};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434363, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434363, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434363}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP002765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PQS8; -.
DR   PeptideAtlas; E9PQS8; -.
DR   Ensembl; ENST00000528267; ENSP00000434363; ENSG00000166257.
DR   UCSC; uc058ipy.1; human.
DR   EuPathDB; HostDB:ENSG00000166257.8; -.
DR   HGNC; HGNC:20665; SCN3B.
DR   OpenTargets; ENSG00000166257; -.
DR   eggNOG; ENOG410IHF3; Eukaryota.
DR   eggNOG; ENOG4111IPM; LUCA.
DR   GeneTree; ENSGT00390000018560; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000166257; Expressed in 135 organ(s), highest expression level in dorsolateral prefrontal cortex.
DR   ExpressionAtlas; E9PQS8; baseline and differential.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0017080; F:sodium channel regulator activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR027098; Na_channel_b1/b3.
DR   InterPro; IPR027096; Na_channel_b3.
DR   PANTHER; PTHR10546; PTHR10546; 1.
DR   PANTHER; PTHR10546:SF1; PTHR10546:SF1; 1.
DR   Pfam; PF07686; V-set; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E9PQS8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25     93       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242910.
FT   DOMAIN       29     91       IGv. {ECO:0000259|Pfam:PF07686}.
FT   NON_TER      93     93       {ECO:0000313|Ensembl:ENSP00000434363}.
SQ   SEQUENCE   93 AA;  10791 MW;  D65075277E9CD59D CRC64;
     MPAFNRLFPL ASLVLIYWVS VCFPVCVEVP SETEAVQGNP MKLRCISCMK REEVEATTVV
     EWFYRPEGGK DFLIYEYRNG HQEVESPFQG RLQ
//