ID   E9PQC8_HUMAN            Unreviewed;       620 AA.
AC   E9PQC8;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 56.
DE   SubName: Full=Immunoglobulin-like domain-containing receptor 2 {ECO:0000313|Ensembl:ENSP00000436882};
GN   Name=ILDR2 {ECO:0000313|Ensembl:ENSP00000436882};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436882, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000436882, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000436882}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL009182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PQC8; -.
DR   jPOST; E9PQC8; -.
DR   PeptideAtlas; E9PQC8; -.
DR   PRIDE; E9PQC8; -.
DR   Ensembl; ENST00000529071; ENSP00000436882; ENSG00000143195.
DR   UCSC; uc057nal.1; human.
DR   EuPathDB; HostDB:ENSG00000143195.12; -.
DR   HGNC; HGNC:18131; ILDR2.
DR   OpenTargets; ENSG00000143195; -.
DR   eggNOG; ENOG410IE5P; Eukaryota.
DR   eggNOG; ENOG410XYIF; LUCA.
DR   GeneTree; ENSGT00940000153958; -.
DR   ChiTaRS; ILDR2; human.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000143195; Expressed in 129 organ(s), highest expression level in testis.
DR   ExpressionAtlas; E9PQC8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR008664; LISCH7.
DR   Pfam; PF05624; LSR; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PQC8,
KW   ECO:0000213|PeptideAtlas:E9PQC8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    620       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245243.
FT   TRANSMEM    163    187       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    166       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   620 AA;  69218 MW;  34CB73208FD12BD9 CRC64;
     MDRVLLRWIS LFWLTAMVEG LQVTVPDKKK VAMLFQPTVL RCHFSTSSHQ PAVVQWKFKS
     YCQDRMGESL GMSSTRAQSL SKRNLEWDPY LDCLDSRRTV RVVASKQGST VTLGDFYRGR
     EITIVHDADL QIGKLMWGDS GLYYCIITTP DDLEGKNEDS VELLVLEWVF VGLVLLGVFL
     FFVLVGICWC QCCPHSCCCY VRCPCCPDSC CCPQALYEAG KAAKAGYPPS VSGVPGPYSI
     PSVPLGGAPS SGMLMDKPHP PPLAPSDSTG GSHSVRKGYR IQADKERDSM KVLYYVEKEL
     AQFDPARRMR GRYNNTISEL SSLHEEDSNF RQSFHQMRSK QFPVSGDLES NPDYWSGVMG
     GSSGASRGPS AMEYNKEDRE SFRHSQPRSK SEMLSRKNFA TGVPAVSMDE LAAFADSYGQ
     RPRRADGNSH EARGGSRFER SESRAHSGFY QDDSLEEYYG QRSRSREPLT DADRGWAFSP
     ARRRPAEDAH LPRLVSRTPG TAPKYDHSYL GSARERQARP EGASRGGSLE TPSKRSAQLG
     PRSASYYAWS PPGTYKAGSS QDDQEDASDD ALPPYSELEL TRGPSYRGRD LPYHSNSEKK
     RKKEPAKKTN DFPTRMSLVV
//