ID   E9PQ42_HUMAN            Unreviewed;       246 AA.
AC   E9PQ42;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 51.
DE   SubName: Full=Cysteine and histidine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000434470};
DE   Flags: Fragment;
GN   Name=CYHR1 {ECO:0000313|Ensembl:ENSP00000434470};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434470, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434470, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434470}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC084125; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PQ42; -.
DR   SMR; E9PQ42; -.
DR   jPOST; E9PQ42; -.
DR   MaxQB; E9PQ42; -.
DR   PeptideAtlas; E9PQ42; -.
DR   PRIDE; E9PQ42; -.
DR   Ensembl; ENST00000526887; ENSP00000434470; ENSG00000187954.
DR   UCSC; uc064rne.1; human.
DR   EuPathDB; HostDB:ENSG00000187954.12; -.
DR   HGNC; HGNC:17806; CYHR1.
DR   OpenTargets; ENSG00000187954; -.
DR   GeneTree; ENSGT00390000018258; -.
DR   ChiTaRS; CYHR1; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000187954; Expressed in 204 organ(s), highest expression level in right testis.
DR   ExpressionAtlas; E9PQ42; baseline and differential.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR039338; CYHR1.
DR   InterPro; IPR008974; TRAF-like.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001293; Znf_TRAF.
DR   PANTHER; PTHR23059; PTHR23059; 1.
DR   SUPFAM; SSF49599; SSF49599; 1.
DR   PROSITE; PS50145; ZF_TRAF; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00207,
KW   ECO:0000256|SAAS:SAAS00449930};
KW   Proteomics identification {ECO:0000213|EPD:E9PQ42,
KW   ECO:0000213|MaxQB:E9PQ42, ECO:0000213|PeptideAtlas:E9PQ42};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00207,
KW   ECO:0000256|SAAS:SAAS00449930};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00207,
KW   ECO:0000256|SAAS:SAAS00449930}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    246       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244177.
FT   DOMAIN       64    122       TRAF-type. {ECO:0000259|PROSITE:PS50145}.
FT   ZN_FING      64    122       TRAF-type. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00207}.
FT   NON_TER     246    246       {ECO:0000313|Ensembl:ENSP00000434470}.
SQ   SEQUENCE   246 AA;  27969 MW;  39E244D0183407E2 CRC64;
     MAPKPGAEWS TALSHLVLGV VSLHAAVSTA ECTNGHLMCA GCFIHLLADA RLKEEQATCP
     NCRCEISKSL CCRNLAVEKA VSELPSECGF CLRQFPRSLL ERHQKEECQD RVTQCKYKRI
     GCPWHGPFHE LTVHEAACAH PTKTGSELME ILDGMDQSHR KEMQLYNSIF SLLSFEKIGY
     TEVQFRPYRT DDFITRLYYE TPRFTVLNQT WVLKARVNDS ERNPNLSCKR TLSFQLLLKS
     KVTAPL
//