ID   E9PPL0_HUMAN            Unreviewed;       437 AA.
AC   E9PPL0;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 52.
DE   SubName: Full=Immunoglobulin-like domain-containing receptor 2 {ECO:0000313|Ensembl:ENSP00000437008};
GN   Name=ILDR2 {ECO:0000313|Ensembl:ENSP00000437008};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000437008, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000437008, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000437008}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL009182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PPL0; -.
DR   jPOST; E9PPL0; -.
DR   PeptideAtlas; E9PPL0; -.
DR   PRIDE; E9PPL0; -.
DR   Ensembl; ENST00000469934; ENSP00000437008; ENSG00000143195.
DR   UCSC; uc057nah.1; human.
DR   EuPathDB; HostDB:ENSG00000143195.12; -.
DR   HGNC; HGNC:18131; ILDR2.
DR   OpenTargets; ENSG00000143195; -.
DR   eggNOG; ENOG410IE5P; Eukaryota.
DR   eggNOG; ENOG410XYIF; LUCA.
DR   GeneTree; ENSGT00940000153958; -.
DR   ChiTaRS; ILDR2; human.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000143195; Expressed in 129 organ(s), highest expression level in testis.
DR   ExpressionAtlas; E9PPL0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR008664; LISCH7.
DR   Pfam; PF05624; LSR; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PPL0,
KW   ECO:0000213|PeptideAtlas:E9PPL0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    437       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245411.
FT   TRANSMEM    187    209       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    166       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   437 AA;  48798 MW;  213B625ACB8504D7 CRC64;
     MDRVLLRWIS LFWLTAMVEG LQVTVPDKKK VAMLFQPTVL RCHFSTSSHQ PAVVQWKFKS
     YCQDRMGESL GMSSTRAQSL SKRNLEWDPY LDCLDSRRTV RVVASKQGST VTLGDFYRGR
     EITIVHDADL QIGKLMWGDS GLYYCIITTP DDLEGKNEDS VELLVLGRTG LLADLLPSFA
     VEIMPEWVFV GLVLLGVFLF FVLVGICWCQ CCPHSCCCYV RCPCCPDSCC CPQALYEAGK
     AAKAGYPPSV SGVPGPYSIP SVPLGGAPSS GMLMDKPHPP PLAPSDSTGG SHSVRKGYRI
     QADKERDSMK VLYYVEKELA QFDPARRMRG RYNNTISELS SLHEEDSNFR QSFHQMRSKQ
     FPVSGDLESN PDYWSGVMGG SSGASRGPSA MEYNKEDRES FRHRMTFQPG CPLWSDVVNI
     SLDNEKSDMD YGDKTQI
//