ID   E9PNX8_HUMAN            Unreviewed;       298 AA.
AC   E9PNX8;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 35.
DE   SubName: Full=von Willebrand factor A domain-containing protein 5B1 {ECO:0000313|Ensembl:ENSP00000437095};
GN   Name=VWA5B1 {ECO:0000313|Ensembl:ENSP00000437095};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000437095, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000437095, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000437095}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL020998; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PNX8; -.
DR   PRIDE; E9PNX8; -.
DR   Ensembl; ENST00000473325; ENSP00000437095; ENSG00000158816.
DR   UCSC; uc057cyu.1; human.
DR   EuPathDB; HostDB:ENSG00000158816.15; -.
DR   HGNC; HGNC:26538; VWA5B1.
DR   OpenTargets; ENSG00000158816; -.
DR   eggNOG; ENOG410IFPF; Eukaryota.
DR   eggNOG; COG2304; LUCA.
DR   GeneTree; ENSGT00940000158938; -.
DR   ChiTaRS; VWA5B1; human.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000158816; Expressed in 51 organ(s), highest expression level in adenohypophysis.
DR   ExpressionAtlas; E9PNX8; baseline and differential.
DR   InterPro; IPR013694; VIT.
DR   Pfam; PF13757; VIT_2; 1.
DR   PROSITE; PS51468; VIT; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    298       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245388.
FT   DOMAIN        1    149       VIT. {ECO:0000259|PROSITE:PS51468}.
SQ   SEQUENCE   298 AA;  31572 MW;  AB387F3B7A0E6C0B CRC64;
     MPGLLNWITG AALPLTASDV TSCVSGYALG LTASLTYGNL EAQPFQGLFV YPLDECTTVI
     GFEAVIADRV VTVQIKDKAK LESGHFDASH VRSPTVTGNI LQDGVSIAPH SCTPGKVTLD
     EDLERILFVA NLGTIAPMEN VTIFISTSSE LPTLPSGAVR VLLPAVCAPT VPQFCTKSTG
     TSNQQAQGKD RHCFGAWAPG SWNKLCLATL LNTEVSNPME YEFNFQLEIR GPCLLAGGEI
     EAAWPWSHCR SGAPNGAGMS LISGLDLGVP QRTPLSPDLM SLYPPCLSMP LRGGESHS
//