ID   E9PMI0_HUMAN            Unreviewed;       262 AA.
AC   E9PMI0;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   SubName: Full=Layilin {ECO:0000313|Ensembl:ENSP00000434972};
GN   Name=LAYN {ECO:0000313|Ensembl:ENSP00000434972};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434972, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434972, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434972}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP002008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PMI0; -.
DR   jPOST; E9PMI0; -.
DR   MaxQB; E9PMI0; -.
DR   PeptideAtlas; E9PMI0; -.
DR   PRIDE; E9PMI0; -.
DR   Ensembl; ENST00000533265; ENSP00000434972; ENSG00000204381.
DR   UCSC; uc058heq.1; human.
DR   EuPathDB; HostDB:ENSG00000204381.11; -.
DR   HGNC; HGNC:29471; LAYN.
DR   OpenTargets; ENSG00000204381; -.
DR   eggNOG; ENOG410IS3Y; Eukaryota.
DR   eggNOG; ENOG410XR2Y; LUCA.
DR   GeneTree; ENSGT00390000001844; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000204381; Expressed in 176 organ(s), highest expression level in decidua.
DR   ExpressionAtlas; E9PMI0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.100.10; -; 1.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   Pfam; PF00059; Lectin_C; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PMI0,
KW   ECO:0000213|PeptideAtlas:E9PMI0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    262       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245165.
FT   TRANSMEM    225    251       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    177       C-type lectin.
FT                                {ECO:0000259|PROSITE:PS50041}.
SQ   SEQUENCE   262 AA;  29585 MW;  4A9707BD048C2418 CRC64;
     MRPGTALQAV LLAVLLVGLR AATGRLLSGQ PVCRGGTQRP CYKVIYFHDT SRRLNFEEAK
     EACRRDGGQL VSIESEDEQK LIEKFIENLL PSDGDFWIGL RRREEKQSNS TACQDLYAWT
     DGSISQFRNW YVDEPSCGSE VCVVMYHQPS APAGIGGPYM FQWNDDRCNM KNNFICKYSD
     EKPAVPSREA EGEETELTTP VLPEETQEED AKKTFKESRE AALNLAYILI PSIPLLLLLV
     VTTVVCWVWI CRKRQKTGAA RP
//