ID   E9PM97_HUMAN            Unreviewed;       104 AA.
AC   E9PM97;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 42.
DE   SubName: Full=Prolyl 4-hydroxylase subunit alpha-3 {ECO:0000313|Ensembl:ENSP00000431227};
GN   Name=P4HA3 {ECO:0000313|Ensembl:ENSP00000431227};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431227, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431227, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431227}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000577; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP001085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PM97; -.
DR   PeptideAtlas; E9PM97; -.
DR   PRIDE; E9PM97; -.
DR   Ensembl; ENST00000525968; ENSP00000431227; ENSG00000149380.
DR   UCSC; uc058fjm.1; human.
DR   EuPathDB; HostDB:ENSG00000149380.11; -.
DR   HGNC; HGNC:30135; P4HA3.
DR   OpenTargets; ENSG00000149380; -.
DR   eggNOG; KOG1591; Eukaryota.
DR   eggNOG; ENOG410XS5J; LUCA.
DR   GeneTree; ENSGT00940000158967; -.
DR   ChiTaRS; P4HA3; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149380; Expressed in 119 organ(s), highest expression level in decidua.
DR   ExpressionAtlas; E9PM97; baseline and differential.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; IEA:InterPro.
DR   InterPro; IPR013547; Pro_4_hyd_alph_N.
DR   Pfam; PF08336; P4Ha_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PM97,
KW   ECO:0000213|PeptideAtlas:E9PM97};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    104       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244139.
FT   DOMAIN       35    103       P4Ha_N. {ECO:0000259|Pfam:PF08336}.
SQ   SEQUENCE   104 AA;  11455 MW;  ACB3D00391343F36 CRC64;
     MGPGARLAAL LAVLALGTGD PERAAARGDT FSALTSVARA LAPERRLLGL LRRYLRGEEA
     RLRDLTRFYD KVLSLHEDST TPVANPLLAF TLIKRLQSDW RNVL
//