ID   E9PM43_HUMAN            Unreviewed;       179 AA.
AC   E9PM43;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 49.
DE   SubName: Full=CD82 antigen {ECO:0000313|Ensembl:ENSP00000433151};
DE   Flags: Fragment;
GN   Name=CD82 {ECO:0000313|Ensembl:ENSP00000433151};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000433151, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000433151, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000433151}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|SAAS:SAAS00595319}.
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DR   EMBL; AC010768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PM43; -.
DR   PeptideAtlas; E9PM43; -.
DR   PRIDE; E9PM43; -.
DR   Ensembl; ENST00000527737; ENSP00000433151; ENSG00000085117.
DR   UCSC; uc058aqw.1; human.
DR   EuPathDB; HostDB:ENSG00000085117.11; -.
DR   HGNC; HGNC:6210; CD82.
DR   OpenTargets; ENSG00000085117; -.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   GeneTree; ENSGT00940000158481; -.
DR   ChiTaRS; CD82; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000085117; Expressed in 230 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; E9PM43; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 2.
DR   PRINTS; PR00259; TMFOUR.
DR   PROSITE; PS00421; TM4_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAAS:SAAS00028005, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PM43,
KW   ECO:0000213|PeptideAtlas:E9PM43};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00028005,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00028005,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     36       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        37    179       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245155.
FT   TRANSMEM     75    100       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    120    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    149    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   NON_TER     179    179       {ECO:0000313|Ensembl:ENSP00000433151}.
SQ   SEQUENCE   179 AA;  19369 MW;  1CF85C758B60E951 CRC64;
     MARDWIRPQR ASDCWSGKQQ LFQIIIIIII SPPCCCVDDT WAQAEVGPVT SCTGFVEGSS
     RTGGMGSACI KVTKYFLFLF NLIFFILGAV ILGFGVWILA DKSSFISVLQ TSSSSLRMGA
     YVFIGVGAVT MLMGFLGCIG AVNEVRCLLG LYFAFLLLIL IAQVTAGALF YFNMGKVSP
//