ID   E9PLN8_HUMAN            Unreviewed;       166 AA.
AC   E9PLN8;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   13-FEB-2019, entry version 57.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000431371};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431371, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431371, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431371}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC135050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PLN8; -.
DR   SMR; E9PLN8; -.
DR   STRING; 9606.ENSP00000431371; -.
DR   BioMuta; ENSG00000255439; -.
DR   EPD; E9PLN8; -.
DR   jPOST; E9PLN8; -.
DR   MaxQB; E9PLN8; -.
DR   PaxDb; E9PLN8; -.
DR   PeptideAtlas; E9PLN8; -.
DR   PRIDE; E9PLN8; -.
DR   Ensembl; ENST00000529564; ENSP00000431371; ENSG00000255439.
DR   UCSC; uc059tkr.1; human.
DR   EuPathDB; HostDB:ENSG00000255439.6; -.
DR   GeneCards; ENSG00000255439; -.
DR   OpenTargets; ENSG00000255439; -.
DR   eggNOG; ENOG410J0HT; Eukaryota.
DR   eggNOG; ENOG4111UX7; LUCA.
DR   GeneTree; ENSGT00940000157421; -.
DR   InParanoid; E9PLN8; -.
DR   PhylomeDB; E9PLN8; -.
DR   TreeFam; TF328467; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000255439; Expressed in 82 organ(s), highest expression level in liver.
DR   ExpressionAtlas; E9PLN8; baseline and differential.
DR   GO; GO:0005783; C:endoplasmic reticulum; IDA:HPA.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR012932; VKOR.
DR   Pfam; PF00089; Trypsin; 1.
DR   Pfam; PF07884; VKOR; 1.
DR   SMART; SM00756; VKc; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     31       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        32    166       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242887.
FT   DOMAIN        5    149       VKc. {ECO:0000259|SMART:SM00756}.
FT   NON_TER     166    166       {ECO:0000313|Ensembl:ENSP00000431371}.
SQ   SEQUENCE   166 AA;  17945 MW;  5CE13C2073D760B2 CRC64;
     MGSTWGSPGW VRLALCLTGL VLSLYALHVK AARARDRDYR ALCDVGTAIS CSRVFSSRWG
     RGFGLVEHVL GQDSILNQSN SIFGCIFYTL QLLLGLQAAQ RACGQRGPGP PKPQEGNTVP
     GEWPWQASVR RQGAHICSGS LVADTWVLTA AHCFEKAAAT ELNSWS
//