ID   E9PL78_HUMAN            Unreviewed;       300 AA.
AC   E9PL78;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 46.
DE   RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};
DE   Flags: Fragment;
GN   Name=TM9SF1 {ECO:0000313|Ensembl:ENSP00000431447};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431447, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431447, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431447}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
CC       {ECO:0000256|RuleBase:RU363079}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU363079}.
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DR   EMBL; AL136295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PL78; -.
DR   STRING; 9606.ENSP00000261789; -.
DR   jPOST; E9PL78; -.
DR   PaxDb; E9PL78; -.
DR   PeptideAtlas; E9PL78; -.
DR   PRIDE; E9PL78; -.
DR   Ensembl; ENST00000528895; ENSP00000431447; ENSG00000100926.
DR   UCSC; uc059abb.1; human.
DR   EuPathDB; HostDB:ENSG00000100926.14; -.
DR   HGNC; HGNC:11864; TM9SF1.
DR   OpenTargets; ENSG00000100926; -.
DR   eggNOG; KOG1277; Eukaryota.
DR   eggNOG; ENOG410XSVB; LUCA.
DR   GeneTree; ENSGT00940000158667; -.
DR   ChiTaRS; TM9SF1; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000100926; Expressed in 127 organ(s), highest expression level in body of pancreas.
DR   ExpressionAtlas; E9PL78; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004240; EMP70.
DR   PANTHER; PTHR10766; PTHR10766; 1.
DR   Pfam; PF02990; EMP70; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU363079};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|RuleBase:RU363079};
KW   Transmembrane {ECO:0000256|RuleBase:RU363079};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363079}.
FT   SIGNAL        1     32       {ECO:0000256|RuleBase:RU363079}.
FT   CHAIN        33    300       Transmembrane 9 superfamily member.
FT                                {ECO:0000256|RuleBase:RU363079}.
FT                                /FTId=PRO_5008192334.
FT   TRANSMEM    236    258       Helical. {ECO:0000256|RuleBase:RU363079}.
FT   NON_TER     300    300       {ECO:0000313|Ensembl:ENSP00000431447}.
SQ   SEQUENCE   300 AA;  34592 MW;  67DA36F078C62A6A CRC64;
     MTVVGNPRSW SCQWLPILIL LLGTGHGPGV EGVTHYKAGD PVILYVNKVG PYHNPQETYH
     YYQLPVCCPE KIRHKSLSLG EVLDGDRMAE SLYEIRFREN VEKRILCHMQ LSSAQVEQLR
     QAIEELYYFE FVVDDLPIRG FVGYMEESGF LPHSHKIGLW THLDFHLEFH GDRIIFANVS
     VRDVKPHSLD GLRPDEFLGL THTYSVRWSE TSVERRSDRR RGDDGGFFPR TLEIHWLSII
     NSMVLVFLLV GFVAVILMRV LRNDLARYNL DEETTSAGSG DDFDQGDNGW KIIHTDVFRF
//