ID   E9PK51_HUMAN            Unreviewed;       158 AA.
AC   E9PK51;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 47.
DE   SubName: Full=Leucine-rich repeat-containing G-protein-coupled receptor 4 {ECO:0000313|Ensembl:ENSP00000431650};
GN   Name=LGR4 {ECO:0000313|Ensembl:ENSP00000431650};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431650, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431650, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431650}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC090597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC100771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PK51; -.
DR   MaxQB; E9PK51; -.
DR   PeptideAtlas; E9PK51; -.
DR   PRIDE; E9PK51; -.
DR   Ensembl; ENST00000480977; ENSP00000431650; ENSG00000205213.
DR   UCSC; uc057zye.1; human.
DR   EuPathDB; HostDB:ENSG00000205213.13; -.
DR   HGNC; HGNC:13299; LGR4.
DR   OpenTargets; ENSG00000205213; -.
DR   GeneTree; ENSGT00940000157925; -.
DR   ChiTaRS; LGR4; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000205213; Expressed in 219 organ(s), highest expression level in liver.
DR   ExpressionAtlas; E9PK51; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR000372; LRRNT.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF01462; LRRNT; 1.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SMART; SM00013; LRRNT; 1.
DR   PROSITE; PS51450; LRR; 4.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS00138699};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PK51,
KW   ECO:0000213|PeptideAtlas:E9PK51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00490532};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    158       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242833.
FT   DOMAIN       28     61       LRRNT. {ECO:0000259|SMART:SM00013}.
SQ   SEQUENCE   158 AA;  16711 MW;  E45A5FA9703D8C72 CRC64;
     MPGPLGLLCF LALGLLGSAG PSGAAPPLCA APCSCDGDRR VDCSGKGLTA VPEGLSAFTQ
     ALDISMNNIT QLPEDAFKNF PFLEELRLDA NHITSVPEDS FEGLVQLRHL WLDDNSLTEV
     PVHPLSNLPT LQALTLALNK ISSIPDFAFT NLSSLVVL
//