ID   E9PJP6_HUMAN            Unreviewed;       141 AA.
AC   E9PJP6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   12-SEP-2018, entry version 46.
DE   SubName: Full=Sodium channel subunit beta-3 {ECO:0000313|Ensembl:ENSP00000435554};
DE   Flags: Fragment;
GN   Name=SCN3B {ECO:0000313|Ensembl:ENSP00000435554};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000435554, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000435554, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000435554}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP002765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PJP6; -.
DR   PeptideAtlas; E9PJP6; -.
DR   Ensembl; ENST00000527836; ENSP00000435554; ENSG00000166257.
DR   UCSC; uc058ipx.1; human.
DR   EuPathDB; HostDB:ENSG00000166257.8; -.
DR   HGNC; HGNC:20665; SCN3B.
DR   OpenTargets; ENSG00000166257; -.
DR   eggNOG; ENOG410IHF3; Eukaryota.
DR   eggNOG; ENOG4111IPM; LUCA.
DR   GeneTree; ENSGT00390000018560; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000166257; Expressed in 135 organ(s), highest expression level in dorsolateral prefrontal cortex.
DR   ExpressionAtlas; E9PJP6; baseline and differential.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0017080; F:sodium channel regulator activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR027098; Na_channel_b1/b3.
DR   InterPro; IPR027096; Na_channel_b3.
DR   PANTHER; PTHR10546; PTHR10546; 1.
DR   PANTHER; PTHR10546:SF1; PTHR10546:SF1; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E9PJP6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    141       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242874.
FT   DOMAIN       24    123       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     141    141       {ECO:0000313|Ensembl:ENSP00000435554}.
SQ   SEQUENCE   141 AA;  16289 MW;  3AF8B1D0FD265E14 CRC64;
     MPAFNRLFPL ASLVLIYWVS VCFPVCVEVP SETEAVQGNP MKLRCISCMK REEVEATTVV
     EWFYRPEGGK DFLIYEYRNG HQEVESPFQG RLQWNGSKDL QDVSITVLNV TLNDSGLYTC
     NVSREFEFEA HRPFVKTTRL I
//