ID   E9PJP3_HUMAN            Unreviewed;        69 AA.
AC   E9PJP3;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Nucleobindin-2 {ECO:0000313|Ensembl:ENSP00000435558};
DE   Flags: Fragment;
GN   Name=NUCB2 {ECO:0000313|Ensembl:ENSP00000435558};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000435558, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000435558, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000435558}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSP00000436215}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [5] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC107956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; E9PJP3; -.
DR   MaxQB; E9PJP3; -.
DR   PeptideAtlas; E9PJP3; -.
DR   PRIDE; E9PJP3; -.
DR   Ensembl; ENST00000526120; ENSP00000436215; ENSG00000070081.
DR   Ensembl; ENST00000533738; ENSP00000435558; ENSG00000070081.
DR   UCSC; uc057zlz.1; human.
DR   EuPathDB; HostDB:ENSG00000070081.15; -.
DR   HGNC; HGNC:8044; NUCB2.
DR   OpenTargets; ENSG00000070081; -.
DR   eggNOG; KOG3866; Eukaryota.
DR   eggNOG; ENOG410XW7D; LUCA.
DR   GeneTree; ENSGT00390000001927; -.
DR   ChiTaRS; NUCB2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000070081; Expressed in 231 organ(s), highest expression level in saliva-secreting gland.
DR   ExpressionAtlas; E9PJP3; baseline and differential.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0032099; P:negative regulation of appetite; IEA:InterPro.
DR   InterPro; IPR028813; NUCB2.
DR   InterPro; IPR040250; Nucleobindin.
DR   PANTHER; PTHR19237; PTHR19237; 1.
DR   PANTHER; PTHR19237:SF22; PTHR19237:SF22; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:E9PJP3,
KW   ECO:0000213|MaxQB:E9PJP3, ECO:0000213|PeptideAtlas:E9PJP3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25     69       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014089025.
FT   NON_TER      69     69       {ECO:0000313|Ensembl:ENSP00000435558}.
SQ   SEQUENCE   69 AA;  8038 MW;  C5449A1CC73AF325 CRC64;
     MRWRTILLQY CFLLITCLLT ALEAVPIDID KTKVQNIHPV ESAKIEPPDT GLYYDEYLKQ
     VIDVLETDK
//