ID   E9PJM1_HUMAN            Unreviewed;       420 AA.
AC   E9PJM1;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 42.
DE   RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};
GN   Name=TM9SF1 {ECO:0000313|Ensembl:ENSP00000431747};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431747, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431747, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431747}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
CC       {ECO:0000256|RuleBase:RU363079}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU363079}.
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DR   EMBL; AL136295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PJM1; -.
DR   jPOST; E9PJM1; -.
DR   MaxQB; E9PJM1; -.
DR   PeptideAtlas; E9PJM1; -.
DR   PRIDE; E9PJM1; -.
DR   Ensembl; ENST00000529332; ENSP00000431747; ENSG00000100926.
DR   UCSC; uc059aay.1; human.
DR   EuPathDB; HostDB:ENSG00000100926.14; -.
DR   HGNC; HGNC:11864; TM9SF1.
DR   OpenTargets; ENSG00000100926; -.
DR   eggNOG; KOG1277; Eukaryota.
DR   eggNOG; KOG1656; Eukaryota.
DR   eggNOG; ENOG410XSVB; LUCA.
DR   GeneTree; ENSGT00940000158667; -.
DR   ChiTaRS; TM9SF1; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000100926; Expressed in 127 organ(s), highest expression level in body of pancreas.
DR   ExpressionAtlas; E9PJM1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004240; EMP70.
DR   PANTHER; PTHR10766; PTHR10766; 1.
DR   Pfam; PF02990; EMP70; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU363079};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|RuleBase:RU363079};
KW   Transmembrane {ECO:0000256|RuleBase:RU363079};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363079}.
FT   SIGNAL        1     32       {ECO:0000256|RuleBase:RU363079}.
FT   CHAIN        33    420       Transmembrane 9 superfamily member.
FT                                {ECO:0000256|RuleBase:RU363079}.
FT                                /FTId=PRO_5007361298.
FT   TRANSMEM    236    258       Helical. {ECO:0000256|RuleBase:RU363079}.
FT   TRANSMEM    306    333       Helical. {ECO:0000256|RuleBase:RU363079}.
FT   TRANSMEM    339    359       Helical. {ECO:0000256|RuleBase:RU363079}.
SQ   SEQUENCE   420 AA;  47553 MW;  A53166CFC84C04F6 CRC64;
     MTVVGNPRSW SCQWLPILIL LLGTGHGPGV EGVTHYKAGD PVILYVNKVG PYHNPQETYH
     YYQLPVCCPE KIRHKSLSLG EVLDGDRMAE SLYEIRFREN VEKRILCHMQ LSSAQVEQLR
     QAIEELYYFE FVVDDLPIRG FVGYMEESGF LPHSHKIGLW THLDFHLEFH GDRIIFANVS
     VRDVKPHSLD GLRPDEFLGL THTYSVRWSE TSVERRSDRR RGDDGGFFPR TLEIHWLSII
     NSMVLVFLLV GFVAVILMRV LRNDLARYNL DEETTSAGSG DDFDQGDNGW KIIHTDVFRF
     PPYRGLLCAV LGVGAQFLAL GTGIIVMALL GMFNVHRHGA INSAAILLYA LTCCISGYVS
     SHFYRQIGGE RWVWNIILTT SLFSGSASHN HPAASDGLAA GGLSPHCHWR HLWEEQRQPL
//