ID   E9PJ02_HUMAN            Unreviewed;        90 AA.
AC   E9PJ02;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 59.
DE   RecName: Full=FXYD domain-containing ion transport regulator {ECO:0000256|RuleBase:RU364131};
GN   Name=FXYD6 {ECO:0000313|Ensembl:ENSP00000431913};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431913, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431913, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431913}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000464144}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FXYD family.
CC       {ECO:0000256|RuleBase:RU364131}.
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DR   EMBL; AP000757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PeptideAtlas; E9PJ02; -.
DR   PRIDE; E9PJ02; -.
DR   Ensembl; ENST00000524841; ENSP00000431913; ENSG00000137726.
DR   Ensembl; ENST00000584230; ENSP00000464144; ENSG00000137726.
DR   UCSC; uc058huw.1; human.
DR   EuPathDB; HostDB:ENSG00000137726.16; -.
DR   HGNC; HGNC:4030; FXYD6.
DR   OpenTargets; ENSG00000137726; -.
DR   eggNOG; ENOG410IZ88; Eukaryota.
DR   eggNOG; ENOG410YUN8; LUCA.
DR   GeneTree; ENSGT00940000153062; -.
DR   OMA; RRCKCNF; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000137726; Expressed in 219 organ(s), highest expression level in cerebellar vermis.
DR   ExpressionAtlas; E9PJ02; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0043269; P:regulation of ion transport; IEA:InterPro.
DR   InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR   Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR   ProDom; PD005989; PD005989; 1.
DR   PROSITE; PS01310; FXYD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Ion transport {ECO:0000256|RuleBase:RU364131};
KW   Membrane {ECO:0000256|RuleBase:RU364131};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|RuleBase:RU364131};
KW   Transmembrane {ECO:0000256|RuleBase:RU364131};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU364131};
KW   Transport {ECO:0000256|RuleBase:RU364131}.
FT   SIGNAL        1     18       {ECO:0000256|RuleBase:RU364131}.
FT   CHAIN        19     90       FXYD domain-containing ion transport
FT                                regulator.
FT                                {ECO:0000256|RuleBase:RU364131}.
FT                                /FTId=PRO_5013982245.
FT   TRANSMEM     36     57       Helical. {ECO:0000256|RuleBase:RU364131}.
SQ   SEQUENCE   90 AA;  9945 MW;  D4277B8414A377FC CRC64;
     MELVLVFLCS LLAPMVLASA AEKEKEMDPF HYDYQTLRIG GLVFAVVLFS VGILLILSRR
     CKCSFNQKPR APGDEEAQVE NLITANGNCP
//