ID   E9PIT6_HUMAN            Unreviewed;        46 AA.
AC   E9PIT6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 52.
DE   SubName: Full=NAD-dependent protein deacetylase sirtuin-3, mitochondrial {ECO:0000313|Ensembl:ENSP00000433899};
GN   Name=SIRT3 {ECO:0000313|Ensembl:ENSP00000433899};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000433899, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000433899, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000433899}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000435014}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC136475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000529055; ENSP00000437179; ENSG00000142082.
DR   Ensembl; ENST00000530067; ENSP00000435014; ENSG00000142082.
DR   Ensembl; ENST00000532837; ENSP00000433899; ENSG00000142082.
DR   UCSC; uc057xcz.1; human.
DR   EuPathDB; HostDB:ENSG00000142082.14; -.
DR   HGNC; HGNC:14931; SIRT3.
DR   OpenTargets; ENSG00000142082; -.
DR   eggNOG; KOG2682; Eukaryota.
DR   eggNOG; COG0846; LUCA.
DR   GeneTree; ENSGT00940000159464; -.
DR   ChiTaRS; SIRT3; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000142082; Expressed in 214 organ(s), highest expression level in anterior cingulate cortex.
DR   ExpressionAtlas; E9PIT6; baseline and differential.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25     46       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014089016.
SQ   SEQUENCE   46 AA;  4982 MW;  D83795E41F566C33 CRC64;
     MAFWGWRAAA ALRLWGRVVE RVEAGGGVGP FQACGCRLVL GGRDDY
//