ID   E9PIT4_HUMAN            Unreviewed;       168 AA.
AC   E9PIT4;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 44.
DE   SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000433906};
DE   Flags: Fragment;
GN   Name=TMEM25 {ECO:0000313|Ensembl:ENSP00000433906};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000433906, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000433906, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000433906}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PIT4; -.
DR   jPOST; E9PIT4; -.
DR   PeptideAtlas; E9PIT4; -.
DR   PRIDE; E9PIT4; -.
DR   Ensembl; ENST00000532762; ENSP00000433906; ENSG00000149582.
DR   UCSC; uc058hzc.1; human.
DR   EuPathDB; HostDB:ENSG00000149582.15; -.
DR   HGNC; HGNC:25890; TMEM25.
DR   OpenTargets; ENSG00000149582; -.
DR   eggNOG; ENOG410IF2Y; Eukaryota.
DR   eggNOG; ENOG410ZNWF; LUCA.
DR   GeneTree; ENSGT00940000154178; -.
DR   ChiTaRS; TMEM25; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149582; Expressed in 150 organ(s), highest expression level in cerebellum.
DR   ExpressionAtlas; E9PIT4; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF08205; C2-set_2; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00504776};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E9PIT4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    168       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245227.
FT   DOMAIN       30    123       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     168    168       {ECO:0000313|Ensembl:ENSP00000433906}.
SQ   SEQUENCE   168 AA;  18140 MW;  D737A6C67500F32F CRC64;
     MALPPGPAAL RHTLLLLPAL LSSGWGELEP QIDGQTWAER ALRENERHAF TCRVAGGPGT
     PRLAWYLDGQ LQEASTSRLL SVGGEAFSGG TSTFTVTAHR AQHELNCSLQ DPRSGRSANA
     SVILNVQCPS RHPSLISSDS NNLKLNNVRL PRENMSLPSN LQLNDLTP
//