ID   E9PI73_HUMAN            Unreviewed;       138 AA.
AC   E9PI73;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 43.
DE   SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000436746};
DE   Flags: Fragment;
GN   Name=TMEM25 {ECO:0000313|Ensembl:ENSP00000436746};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436746, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000436746, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000436746}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP000941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PI73; -.
DR   PeptideAtlas; E9PI73; -.
DR   Ensembl; ENST00000533689; ENSP00000436746; ENSG00000149582.
DR   UCSC; uc058hzl.1; human.
DR   EuPathDB; HostDB:ENSG00000149582.15; -.
DR   HGNC; HGNC:25890; TMEM25.
DR   OpenTargets; ENSG00000149582; -.
DR   eggNOG; ENOG410IF2Y; Eukaryota.
DR   eggNOG; ENOG410ZNWF; LUCA.
DR   GeneTree; ENSGT00940000154178; -.
DR   ChiTaRS; TMEM25; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149582; Expressed in 150 organ(s), highest expression level in cerebellum.
DR   ExpressionAtlas; E9PI73; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF08205; C2-set_2; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00504776};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E9PI73};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    138       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244073.
FT   DOMAIN       30    123       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     138    138       {ECO:0000313|Ensembl:ENSP00000436746}.
SQ   SEQUENCE   138 AA;  14742 MW;  A740087272990058 CRC64;
     MALPPGPAAL RHTLLLLPAL LSSGWGELEP QIDGQTWAER ALRENERHAF TCRVAGGPGT
     PRLAWYLDGQ LQEASTSRLL SVGGEAFSGG TSTFTVTAHR AQHELNCSLQ DPRSGRSANA
     SVILNVQFKP EIAQVGAK
//