ID   E9PF05_HUMAN            Unreviewed;       242 AA.
AC   E9PF05;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 54.
DE   SubName: Full=Formylglycine-generating enzyme {ECO:0000313|Ensembl:ENSP00000410060};
GN   Name=SUMF1 {ECO:0000313|Ensembl:ENSP00000410060};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000410060, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000410060, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000410060}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC018822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC023480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC023484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC024167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF454952; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF454953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF457530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PF05; -.
DR   SMR; E9PF05; -.
DR   jPOST; E9PF05; -.
DR   MaxQB; E9PF05; -.
DR   PeptideAtlas; E9PF05; -.
DR   PRIDE; E9PF05; -.
DR   Ensembl; ENST00000458465; ENSP00000410060; ENSG00000144455.
DR   UCSC; uc011ast.3; human.
DR   EuPathDB; HostDB:ENSG00000144455.13; -.
DR   HGNC; HGNC:20376; SUMF1.
DR   OpenTargets; ENSG00000144455; -.
DR   eggNOG; ENOG410IEYZ; Eukaryota.
DR   eggNOG; COG1262; LUCA.
DR   GeneTree; ENSGT00390000008983; -.
DR   ChiTaRS; SUMF1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000144455; Expressed in 209 organ(s), highest expression level in metanephros.
DR   ExpressionAtlas; E9PF05; baseline and differential.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR005532; SUMF_dom.
DR   Pfam; PF03781; FGE-sulfatase; 2.
DR   SUPFAM; SSF56436; SSF56436; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:E9PF05,
KW   ECO:0000213|MaxQB:E9PF05, ECO:0000213|PeptideAtlas:E9PF05};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     33       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        34    242       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003242827.
FT   DOMAIN       89    147       FGE-sulfatase.
FT                                {ECO:0000259|Pfam:PF03781}.
FT   DOMAIN      148    235       FGE-sulfatase.
FT                                {ECO:0000259|Pfam:PF03781}.
SQ   SEQUENCE   242 AA;  25707 MW;  EE0B287348E07E23 CRC64;
     MAAPALGLVC GRCPELGLVL LLLLLSLLCG AAGSQEAGTG AGAGSLAGSC GCGTPQRPGA
     HGSSAAAHRY SREANAPGPV PGERQLAHSK MVPIPAGVFT MGTDDPQIKQ DGEAPARRVT
     IDAFYMDAYE VSNTEFEKFV NSTGYLTEVD AFPPNGYGLY NIVGNAWEWT SDWWTVHHSV
     EETLNPKGPP SGKDRVKKGG SYMCHRSYCY RYRCAARSQN TPDSSASNLG FRCAADRLPT
     MD
//