ID   E9PEI6_HUMAN            Unreviewed;      1393 AA.
AC   E9PEI6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   13-FEB-2019, entry version 57.
DE   SubName: Full=DPCR1 {ECO:0000313|EMBL:AQY76787.1};
DE   SubName: Full=Mucin-like protein 3 {ECO:0000313|Ensembl:ENSP00000417182};
GN   Name=MUCL3 {ECO:0000313|Ensembl:ENSP00000417182};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000417182, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000417182, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000417182}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:AQY76787.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Norman P.J., Norberg S.J., Nemat-Gorgani N., Ronaghi M., Parham P.;
RT   "CDS alleles of MHC region genes derived from homozygous
RT   individuals.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AL669830; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KY500299; AQY76787.1; -; Genomic_DNA.
DR   RefSeq; NP_543146.2; NM_080870.3.
DR   UniGene; Hs.631993; -.
DR   ProteinModelPortal; E9PEI6; -.
DR   STRING; 9606.ENSP00000417182; -.
DR   EPD; E9PEI6; -.
DR   jPOST; E9PEI6; -.
DR   DNASU; 135656; -.
DR   Ensembl; ENST00000462446; ENSP00000417182; ENSG00000168631.
DR   GeneID; 135656; -.
DR   KEGG; hsa:135656; -.
DR   UCSC; uc003nsg.3; human.
DR   CTD; 135656; -.
DR   EuPathDB; HostDB:ENSG00000168631.11; -.
DR   HGNC; HGNC:21666; MUCL3.
DR   OpenTargets; ENSG00000168631; -.
DR   eggNOG; ENOG410J4CW; Eukaryota.
DR   eggNOG; ENOG411268F; LUCA.
DR   GeneTree; ENSGT00390000016847; -.
DR   OrthoDB; 840286at2759; -.
DR   PhylomeDB; E9PEI6; -.
DR   TreeFam; TF338742; -.
DR   ChiTaRS; DPCR1; human.
DR   GenomeRNAi; 135656; -.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000168631; Expressed in 39 organ(s), highest expression level in stomach.
DR   ExpressionAtlas; E9PEI6; baseline and differential.
DR   Genevisible; E9PEI6; HS.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026623; MUCL3.
DR   PANTHER; PTHR22094; PTHR22094; 12.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E9PEI6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30   1393       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014571001.
FT   TRANSMEM   1322   1346       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   1393 AA;  151168 MW;  28DC6BAE8990AD87 CRC64;
     MAQPVHSLCS AFGLQCCLLF LLASWGAGAT TFQEYQKTGE LSTSDHIFPL TPGLVYSIPF
     DHIVLHSGQR PPELPKSTEI HEQKRHCNTT RHSKPTDKPT GNSKTIDHKS STDNHEAPPT
     SEENSSNQGK DPMIRNQRSV DPADSTTTHK ESAGKKHITP APKSKINCRK STTGKSTVTR
     KSDKTGRPLE KSMSTLDKTS TSSHKTTTSF HNSGNSQTKQ KSTSFPEKIT AASKTTYKTT
     GTPEESEKTE DSRTTVASDK LLTKTTKNIQ ETISANELTQ SLAEPTEHGG RTANENNTPS
     PAEPTENRER TANENTTLSP AEPIENRERT ANENTAPFPA GPTENREMTA NENTTLFPAE
     PTEHGERTAN ENTTPSPAEP TEHGERTANE NTTPSPAEPT EHGERTPFAN DKTTSSSAES
     TEHGERTPLA NENTTPSPAE PTENRERTAN ENTTPSPAGP TENRETTANE KTTLSPVEPT
     ENRETTANEK TTPSPAEPTE NGQRTPFANE KTTSSSAEPT EHGERTPLAN ENTTPSPAEP
     TENRERTANE KTTPSPAEPT ENGDRTPLAN EKTTPSLAEP TENGQRTPFA NEKTTSSSAE
     PTEHEERTPL ANENTTPSPA EPTENRERTA NENTTPSPAG PTENREMTAN EKTTLFPAEP
     TENRERTANE KTTSSPAEPT ENGQRTPFAN EKTTSSSAEP TEHGERTPLA NENTTLSPAE
     PTENRERTAN EKTTPFPAEP TENRERTANE NTTPSPAQPT ENGDRTPLAN EKTTPSLAEP
     TENGKRTPFA NEKTTSSSAE PTEHAERTPL ANENTTSSPA EPTENRERTA NEKTTQFPAE
     PTENRESTAN EKTTPFPAEP TENREWTANE NTTLSPAEPT EHEEMTPLAN EKTTLSPAEP
     TENGERTPFT NEKTTPSSAE PTEHGERTPL ANEITTPSRA EPTEHGERIA NEKATPSPAK
     PTEHGETTVN EDTTPSSAEP TENGERTPLA NENTTTSPTE STEHGERTAN EKTTPSPAEP
     TEHGERTPSA NEKTIPSPAK PTEHEEMTPS ANENTTPSPV KPTEHGEKTT LANEKITLSP
     EGPTEHGAKT TSANEKITPS LAKPTEHGER TTSPNDKITS SAAESTEHRD RATSANVITP
     APAEPIKHAK RTTLAHEKMT QVTEKSTEHP EKTTSTTEKT TRTPEKPTLY SEKTICTKGK
     NTPVPEKPTE NLGNTTLTTE TIKAPVKSTE NPEKTAAVTK TIKPSVKVTG DKSLTTTSSH
     LNKTEVTHQV PTGSFTLITS RTKLSSITSE ATGNESHPYL NKDGSQKGIH AGQMGENDSF
     PAWAIVIVVL VAVILLLVFL GLIFLVSYMM RTRRTLTQNT QYNDAEDEGG PNSYPVYLME
     QQNLGMGQIP SPR
//