ID   E9PDQ1_HUMAN            Unreviewed;       177 AA.
AC   E9PDQ1;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   12-SEP-2018, entry version 57.
DE   SubName: Full=Alpha-S1-casein {ECO:0000313|Ensembl:ENSP00000427490};
GN   Name=CSN1S1 {ECO:0000313|Ensembl:ENSP00000427490};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000427490, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000427490, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000213|PubMed:20068231}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA   Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA   Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S.,
RA   Mann M.;
RT   "Quantitative phosphoproteomics reveals widespread full
RT   phosphorylation site occupancy during mitosis.";
RL   Sci. Signal. 3:ra3-RA3(2010).
RN   [3] {ECO:0000313|Ensembl:ENSP00000427490}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2012) to UniProtKB.
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DR   EMBL; AC108941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PDQ1; -.
DR   Allergome; 1064; Hom s 8.
DR   PeptideAtlas; E9PDQ1; -.
DR   PRIDE; E9PDQ1; -.
DR   Ensembl; ENST00000507772; ENSP00000427490; ENSG00000126545.
DR   UCSC; uc062xbp.1; human.
DR   EuPathDB; HostDB:ENSG00000126545.13; -.
DR   HGNC; HGNC:2445; CSN1S1.
DR   OpenTargets; ENSG00000126545; -.
DR   GeneTree; ENSGT00390000017378; -.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000126545; Expressed in 72 organ(s), highest expression level in layer of synovial tissue.
DR   ExpressionAtlas; E9PDQ1; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   InterPro; IPR026999; Alpha-s1_casein.
DR   InterPro; IPR031305; Casein_CS.
DR   PANTHER; PTHR10240; PTHR10240; 2.
DR   PROSITE; PS00306; CASEIN_ALPHA_BETA; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PDQ1,
KW   ECO:0000213|PeptideAtlas:E9PDQ1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    177       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5013152836.
FT   COILED      101    121       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   177 AA;  20821 MW;  78B120E9794B63C5 CRC64;
     MRLLILTCLV AVALARPKLP LRYPERLQNP SESSEPIPLE SREEYMNGMN RQRNILREKQ
     TDEIKDTRNE STQNCVVAEP EKMESSISSS SEEQFCRLNE YNQLQLQAAH AQEQIRRMNE
     NSHVQVPFQQ LNQLAAYPYA VWYYPQIMQY VPFPPFSDIS NPTAHENYEK NNVMLQW
//