ID   E9PB98_HUMAN            Unreviewed;        73 AA.
AC   E9PB98;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-DEC-2018, entry version 40.
DE   SubName: Full=Sodium/calcium exchanger 1 {ECO:0000313|Ensembl:ENSP00000412560};
DE   Flags: Fragment;
GN   Name=SLC8A1 {ECO:0000313|Ensembl:ENSP00000412560};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000412560, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000412560, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000412560}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC007254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC007377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF459834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF459835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF459836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF495765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PB98; -.
DR   PRIDE; E9PB98; -.
DR   Ensembl; ENST00000417271; ENSP00000412560; ENSG00000183023.
DR   UCSC; uc061iod.1; human.
DR   EuPathDB; HostDB:ENSG00000183023.18; -.
DR   HGNC; HGNC:11068; SLC8A1.
DR   OpenTargets; ENSG00000183023; -.
DR   eggNOG; KOG1306; Eukaryota.
DR   eggNOG; ENOG410XPJP; LUCA.
DR   GeneTree; ENSGT00940000155129; -.
DR   ChiTaRS; SLC8A1; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000183023; Expressed in 201 organ(s), highest expression level in heart.
DR   ExpressionAtlas; E9PB98; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; IEA:InterPro.
DR   InterPro; IPR002987; NaCa_exhngr1.
DR   PRINTS; PR01260; NACAEXCHNGR1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     35       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        36     73       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003245088.
FT   NON_TER      73     73       {ECO:0000313|Ensembl:ENSP00000412560}.
SQ   SEQUENCE   73 AA;  8200 MW;  274E9743538FAB6E CRC64;
     MYNMRRLSLS PTFSMGFHLL VTVSLLFSHV DHVIAETEME GEGNETGECT GSYYCKKGVI
     LPIWEPQDPS FGD
//