ID   E9PB18_HUMAN            Unreviewed;       901 AA.
AC   E9PB18;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   SubName: Full=UPF0577 protein KIAA1324 {ECO:0000313|Ensembl:ENSP00000393964};
DE   Flags: Fragment;
GN   Name=KIAA1324 {ECO:0000313|Ensembl:ENSP00000393964};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000393964, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000393964, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000393964}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL138933; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL356389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PB18; -.
DR   jPOST; E9PB18; -.
DR   PeptideAtlas; E9PB18; -.
DR   PRIDE; E9PB18; -.
DR   Ensembl; ENST00000457623; ENSP00000393964; ENSG00000116299.
DR   UCSC; uc057ixr.1; human.
DR   EuPathDB; HostDB:ENSG00000116299.16; -.
DR   HGNC; HGNC:29618; KIAA1324.
DR   OpenTargets; ENSG00000116299; -.
DR   GeneTree; ENSGT00940000156861; -.
DR   ChiTaRS; KIAA1324; human.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000116299; Expressed in 153 organ(s), highest expression level in parotid gland.
DR   ExpressionAtlas; E9PB18; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:HPA.
DR   Gene3D; 2.70.130.10; -; 1.
DR   InterPro; IPR039181; EIG121-like.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR   InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR   PANTHER; PTHR22727; PTHR22727; 2.
DR   SMART; SM01411; Ephrin_rec_like; 3.
DR   SUPFAM; SSF57184; SSF57184; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PB18,
KW   ECO:0000213|PeptideAtlas:E9PB18};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     41       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        42    901       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003244978.
FT   TRANSMEM    857    881       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       88    121       Ephrin_rec_like.
FT                                {ECO:0000259|SMART:SM01411}.
FT   DOMAIN      335    387       Ephrin_rec_like.
FT                                {ECO:0000259|SMART:SM01411}.
FT   DOMAIN      558    608       Ephrin_rec_like.
FT                                {ECO:0000259|SMART:SM01411}.
FT   NON_TER     901    901       {ECO:0000313|Ensembl:ENSP00000393964}.
SQ   SEQUENCE   901 AA;  99366 MW;  B1EC3AB800C21852 CRC64;
     MAEPGHSHHL SARVRGRTER RIPRLWRLLL WAGTAFQVTQ GTGPELHACK ESEYHYEYTA
     CDSTGSRWRV AVPHTPGLCT SLPDPIKGTE CSFSCNAGEF LDMKDQSCKP CAEGRYSLGT
     GIRFDEWDEL PHGFASLSAN MELDDSAAES TGNCTSSKWV PRGDYIASNT DECTATLMYA
     VNLKQSGTVN FEYYYPDSSI IFEFFVQNDQ CQPNADDSRW MKTTEKGWEF HSVELNRGNN
     VLYWRTTAFS VWTKVPKPVL VRNIAITEKG SSSCNVRPAC TDKDYFYTHT ACDANGETQL
     MYKWAKPKIC SEDLEGAVKL PASGVKTHCP PCNPGFFKTN NSTCQPCPYG SYSNGSDCTR
     CPAGTEPAVG FEYKWWNTLP TNMETTVLSG INFEYKGMTG WEVAGDHIYT AAGASDNDFM
     ILTLVVPGFR PPQSVMADTE NKEVARITFV FETLCSVNCE LYFMVGVNSR TNTPVETWKG
     SKGKQSYTYI IEENTTTSFT WAFQRTTFHE ASRKYTNDVA KIYSINVTNV MNGVASYCRP
     CALEASDVGS SCTSCPAGYY IDRDSGTCHS CPTNTILKAH QPYGVQACVP CGPGTKNNKI
     HSLCYNDCTF SRNTPTRTFN YNFSALANTV TLAGGPSFTS KGLKYFHHFT LSLCGNQGRK
     MSVCTDNVTD LRIPEGESGF SKSITAYVCQ AVIIPPEVTG YKAGVSSQPV SLADRLIGVT
     TDMTLDGITS PAELFHLESL GIPDVIFFYR SNDVTQSCSS GRSTTIRVRC SPQKTVPGSL
     LLPGTCSDGT CDGCNFHFLW ESAAACPLCS VADYHAIVSS CVAGIQKTTY VWREPKLCSG
     GISLPEQRVT ICKTIDFWLK VGISAGTCTA ILLTVLTCYF WKKNQKLEYK YSKLVMNATL
     K
//