ID   E7EU04_HUMAN            Unreviewed;       210 AA.
AC   E7EU04;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 2.
DT   16-JAN-2019, entry version 47.
DE   SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000321957};
DE   Flags: Fragment;
GN   Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000321957};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000321957, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000321957, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000321957}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E7EU04; -.
DR   SMR; E7EU04; -.
DR   jPOST; E7EU04; -.
DR   PeptideAtlas; E7EU04; -.
DR   PRIDE; E7EU04; -.
DR   Ensembl; ENST00000321324; ENSP00000321957; ENSG00000165457.
DR   UCSC; uc058faf.1; human.
DR   EuPathDB; HostDB:ENSG00000165457.13; -.
DR   HGNC; HGNC:3793; FOLR2.
DR   OpenTargets; ENSG00000165457; -.
DR   eggNOG; ENOG410IFFP; Eukaryota.
DR   eggNOG; ENOG4111IU4; LUCA.
DR   GeneTree; ENSGT00940000153758; -.
DR   ChiTaRS; FOLR2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000165457; Expressed in 215 organ(s), highest expression level in esophagus.
DR   ExpressionAtlas; E7EU04; baseline and differential.
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0061714; F:folic acid receptor activity; IEA:InterPro.
DR   GO; GO:1904447; P:folate import across plasma membrane; IEA:InterPro.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR032937; FOLR2.
DR   PANTHER; PTHR10517; PTHR10517; 1.
DR   PANTHER; PTHR10517:SF8; PTHR10517:SF8; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E7EU04,
KW   ECO:0000213|PeptideAtlas:E7EU04};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     34       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        35    210       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003219501.
FT   DOMAIN       43    208       Folate_rec. {ECO:0000259|Pfam:PF03024}.
FT   NON_TER     210    210       {ECO:0000313|Ensembl:ENSP00000321957}.
SQ   SEQUENCE   210 AA;  24363 MW;  69905AEAC618CB0C CRC64;
     MLPAATEVQG QKDMVWKWMP LLLLLVCVAT MCSAQDRTDL LNVCMDAKHH KTKPGPEDKL
     HDQCSPWKKN ACCTASTSQE LHKDTSRLYN FNWDHCGKME PACKRHFIQD TCLYECSPNL
     GPWIQQVNQS WRKERFLDVP LCKEDCQRWW EDCHTSHTCK SNWHRGWDWT SGVNKCPAGA
     LCRTFESYFP TPAALCEGLW SHSYKVSNYS
//