ID   E7EPM8_HUMAN            Unreviewed;       351 AA.
AC   E7EPM8; E7EPU8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 2.
DT   12-SEP-2018, entry version 45.
DE   SubName: Full=Stereocilin {ECO:0000313|Ensembl:ENSP00000394866};
GN   Name=STRC {ECO:0000313|Ensembl:ENSP00000394866};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000394866, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000394866, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000394866}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC011330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E7EPM8; -.
DR   PeptideAtlas; E7EPM8; -.
DR   Ensembl; ENST00000440125; ENSP00000394866; ENSG00000242866.
DR   UCSC; uc059ill.1; human.
DR   EuPathDB; HostDB:ENSG00000242866.9; -.
DR   HGNC; HGNC:16035; STRC.
DR   OpenTargets; ENSG00000242866; -.
DR   eggNOG; ENOG410IIWF; Eukaryota.
DR   eggNOG; ENOG410ZQVX; LUCA.
DR   GeneTree; ENSGT00530000063809; -.
DR   ChiTaRS; STRC; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000242866; Expressed in 107 organ(s), highest expression level in right hemisphere of cerebellum.
DR   ExpressionAtlas; E7EPM8; baseline and differential.
DR   InterPro; IPR026061; Stereocilin.
DR   InterPro; IPR026664; Stereocilin-rel.
DR   PANTHER; PTHR23412; PTHR23412; 1.
DR   PANTHER; PTHR23412:SF14; PTHR23412:SF14; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    351       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003217317.
SQ   SEQUENCE   351 AA;  37319 MW;  0956CEF3BE6DB15A CRC64;
     MALSLWPLLL LLLLLLLLSF AVTLAPTGPH SLDPGLSFLK SLLSTLDQAP QGSLSRSRFF
     TFLANISSSF EPGRMGEGPV GEPPPLQPPA LRLHDFLVTL RGSPDWEPML GLLGDMLALL
     GQEQTPRDFL VHQAGVLGGL VEVLLGALVP GGPPTPTRPP CTRDGPSDCV LAADWLPSLL
     LLLEGTRWQA LVQVQPSVDP TNATGLDGRE AAPHFLQGLL GLLTPTGELG SKEALWGGLL
     RTVGAPLYAA FQEGLLRVTH SLQDEVFSIL GQPEPDTNGQ CQGGNLQQLL LWGVRHNLSW
     DVQALGFLSG SPPPPPALLH CLSTGVPLPR ASQPSAHISP RQRRAITVEA L
//