ID   E7ENM0_HUMAN            Unreviewed;       706 AA.
AC   E7ENM0;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   16-JAN-2019, entry version 49.
DE   SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000389857};
GN   Name=ELN {ECO:0000313|Ensembl:ENSP00000389857};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000389857, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000389857, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000389857}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC005056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001265841.1; NM_001278912.1.
DR   UniGene; Hs.647061; -.
DR   ProteinModelPortal; E7ENM0; -.
DR   Allergome; 11040; Hom s Elastin.
DR   jPOST; E7ENM0; -.
DR   PeptideAtlas; E7ENM0; -.
DR   PRIDE; E7ENM0; -.
DR   Ensembl; ENST00000445912; ENSP00000389857; ENSG00000049540.
DR   GeneID; 2006; -.
DR   UCSC; uc011kff.4; human.
DR   CTD; 2006; -.
DR   EuPathDB; HostDB:ENSG00000049540.16; -.
DR   HGNC; HGNC:3327; ELN.
DR   OpenTargets; ENSG00000049540; -.
DR   eggNOG; ENOG410IZT8; Eukaryota.
DR   eggNOG; ENOG4111817; LUCA.
DR   GeneTree; ENSGT00730000111510; -.
DR   OrthoDB; 930292at2759; -.
DR   ChiTaRS; ELN; human.
DR   GenomeRNAi; 2006; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000049540; Expressed in 181 organ(s), highest expression level in thoracic aorta.
DR   ExpressionAtlas; E7ENM0; baseline and differential.
DR   GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   InterPro; IPR003979; Tropoelastin.
DR   PANTHER; PTHR24018; PTHR24018; 3.
DR   PRINTS; PR01500; TROPOELASTIN.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E7ENM0,
KW   ECO:0000213|PeptideAtlas:E7ENM0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    706       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003219423.
SQ   SEQUENCE   706 AA;  61154 MW;  34BF630B341E2F50 CRC64;
     MAGLTAAAPR PGVLLLLLSI LHPSRPGGVP GAIPGGVPGG VFYPGAGLGA LGGGALGPGG
     KPLKPVPGGL AGAGLGAGLG AFPAVTFPGA LVPGGVADAA AAYKAAKAGA GLGGVPGVGG
     LGVSAGAVVP QPGAGVKPGK VPGVGLPGVY PGGVLPGARF PGVGVLPGVP TGAGVKPKAP
     GVGGAFAGIP GVGPFGGPQP GVPLGYPIKA PKLPGGYGLP YTTGKLPYGY GPGGVAGAAG
     KAGYPTGTGV GPQAAAAAAA KAAAKFGAGA AGVLPGVGGA GVPGVPGAIP GIGGIAGVGT
     PAAAAAAAAA AKAAKYGAAA GLVPGGPGFG PGVVGVPGAG VPGVGVPGAG IPVVPGAGIP
     GAAVPGVVSP EAAAKAAAKA AKYGARPGVG VGGIPTYGVG AGGFPGFGVG VGGIPGVAGV
     PGVGGVPGVG GVPGVGISPE AQAAAAAKAA KYGVGTPAAA AAKAAAKAAQ FGLVPGVGVA
     PGVGVAPGVG VAPGVGLAPG VGVAPGVGVA PGVGVAPGIG PGGVAAAAKS AAKVAAKAQL
     RAAAGLGAGI PGLGVGVGVP GLGVGAGVPG LGVGAGVPGF GAVPGALAAA KAAKYGAAVP
     GVLGGLGALG GVGIPGGVVG AGPAAAAAAA KAAAKAAQFG LVGAAGLGGL GVGGLGVPGV
     GGLGGIPPAA AAKAAKYGVA ARPGFGLSPI FPGGACLGKA CGRKRK
//