ID   E7EN01_HUMAN            Unreviewed;        77 AA.
AC   E7EN01;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   05-DEC-2018, entry version 54.
DE   SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000415626};
DE   Flags: Fragment;
GN   Name=CALCRL {ECO:0000313|Ensembl:ENSP00000415626};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000415626, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000415626, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000415626}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC007319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC074020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E7EN01; -.
DR   PeptideAtlas; E7EN01; -.
DR   PRIDE; E7EN01; -.
DR   Ensembl; ENST00000447403; ENSP00000415626; ENSG00000064989.
DR   UCSC; uc061qmm.1; human.
DR   EuPathDB; HostDB:ENSG00000064989.12; -.
DR   HGNC; HGNC:16709; CALCRL.
DR   OpenTargets; ENSG00000064989; -.
DR   eggNOG; KOG4564; Eukaryota.
DR   eggNOG; ENOG410XRS2; LUCA.
DR   GeneTree; ENSGT00940000159898; -.
DR   ChiTaRS; CALCRL; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000064989; Expressed in 181 organ(s), highest expression level in lung.
DR   ExpressionAtlas; E7EN01; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004948; F:calcitonin receptor activity; IEA:InterPro.
DR   Gene3D; 4.10.1240.10; -; 1.
DR   InterPro; IPR003287; GCPR_2_calcitonin_rcpt_fam.
DR   InterPro; IPR003289; GPCR_2_CGRP1_rcpt.
DR   InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR   InterPro; IPR001879; GPCR_2_extracellular_dom.
DR   PRINTS; PR01351; CGRPRECEPTOR.
DR   PRINTS; PR01350; CTRFAMILY.
DR   SUPFAM; SSF111418; SSF111418; 1.
DR   PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E7EN01,
KW   ECO:0000213|PeptideAtlas:E7EN01};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23     77       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008413852.
FT   DOMAIN       47     77       G_PROTEIN_RECEP_F2_3.
FT                                {ECO:0000259|PROSITE:PS50227}.
FT   NON_TER      77     77       {ECO:0000313|Ensembl:ENSP00000415626}.
SQ   SEQUENCE   77 AA;  9132 MW;  E8CC815DF69E3E99 CRC64;
     MEKKCTLYFL VLLPFFMILV TAELEESPED SIQLGVTRNK IMTAQYECYQ KIMQDPIQQA
     EGVYCNRTWD GWLCWND
//