ID   E5RJT4_HUMAN            Unreviewed;        64 AA.
AC   E5RJT4;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   05-DEC-2018, entry version 55.
DE   SubName: Full=Frizzled-6 {ECO:0000313|Ensembl:ENSP00000428188};
GN   Name=FZD6 {ECO:0000313|Ensembl:ENSP00000428188};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000428188, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000428188, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000428188}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC025370; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E5RJT4; -.
DR   PeptideAtlas; E5RJT4; -.
DR   PRIDE; E5RJT4; -.
DR   Ensembl; ENST00000521195; ENSP00000428188; ENSG00000164930.
DR   UCSC; uc064pin.1; human.
DR   EuPathDB; HostDB:ENSG00000164930.11; -.
DR   HGNC; HGNC:4044; FZD6.
DR   OpenTargets; ENSG00000164930; -.
DR   eggNOG; KOG3577; Eukaryota.
DR   eggNOG; ENOG410XRC8; LUCA.
DR   GeneTree; ENSGT00940000158485; -.
DR   ChiTaRS; FZD6; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000164930; Expressed in 199 organ(s), highest expression level in bronchial epithelial cell.
DR   ExpressionAtlas; E5RJT4; baseline and differential.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.2000.10; -; 1.
DR   InterPro; IPR015526; Frizzled/SFRP.
DR   InterPro; IPR036790; Frizzled_dom_sf.
DR   InterPro; IPR026543; FZD6.
DR   PANTHER; PTHR11309; PTHR11309; 1.
DR   PANTHER; PTHR11309:SF75; PTHR11309:SF75; 1.
DR   SUPFAM; SSF63501; SSF63501; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19     64       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003198434.
SQ   SEQUENCE   64 AA;  7328 MW;  53E4E95BAB60E3A8 CRC64;
     MEMFTFLLTC IFLPLLRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QSIAAVEMEG
     TQTG
//