ID   E5RIF6_HUMAN            Unreviewed;       223 AA.
AC   E5RIF6;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   05-DEC-2018, entry version 42.
DE   SubName: Full=Hepatitis A virus cellular receptor 1 {ECO:0000313|Ensembl:ENSP00000428422};
DE   Flags: Fragment;
GN   Name=HAVCR1 {ECO:0000313|Ensembl:ENSP00000428422};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000428422, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000428422, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000428422}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC026777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E5RIF6; -.
DR   SMR; E5RIF6; -.
DR   MaxQB; E5RIF6; -.
DR   PeptideAtlas; E5RIF6; -.
DR   PRIDE; E5RIF6; -.
DR   Ensembl; ENST00000518745; ENSP00000428422; ENSG00000113249.
DR   UCSC; uc063jbt.1; human.
DR   EuPathDB; HostDB:ENSG00000113249.12; -.
DR   HGNC; HGNC:17866; HAVCR1.
DR   OpenTargets; ENSG00000113249; -.
DR   eggNOG; ENOG410IZDR; Eukaryota.
DR   eggNOG; ENOG410YSF7; LUCA.
DR   GeneTree; ENSGT00940000159345; -.
DR   ChiTaRS; HAVCR1; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000113249; Expressed in 77 organ(s), highest expression level in adult mammalian kidney.
DR   ExpressionAtlas; E5RIF6; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E5RIF6,
KW   ECO:0000213|PeptideAtlas:E5RIF6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    223       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003198402.
FT   DOMAIN        3    121       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     223    223       {ECO:0000313|Ensembl:ENSP00000428422}.
SQ   SEQUENCE   223 AA;  23872 MW;  2E5BE19190E1AC00 CRC64;
     MHPQVVILSL ILHLADSVAG SVKVGGEAGP SVTLPCHYSG AVTSMCWNRG SCSLFTCQNG
     IVWTNGTHVT YRKDTRYKLL GDLSRRDVSL TIENTAVSDS GVYCCRVEHR GWFNDMKITV
     SLEIVPPKVT TTPIVTTVPT VTTVRTSTTV PTTTTVPMTT VPTTTVPTTM SIPTTTTVLT
     TMTVSTTTSV PTTTSIPTTT SVPVTTTVST FVPPMPLPRQ NHE
//