ID   E5RGU9_HUMAN            Unreviewed;        76 AA.
AC   E5RGU9;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   05-DEC-2018, entry version 45.
DE   SubName: Full=R-spondin-2 {ECO:0000313|Ensembl:ENSP00000430973};
DE   Flags: Fragment;
GN   Name=RSPO2 {ECO:0000313|Ensembl:ENSP00000430973};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000430973, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000430973, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000430973}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC025508; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E5RGU9; -.
DR   PRIDE; E5RGU9; -.
DR   Ensembl; ENST00000522333; ENSP00000430973; ENSG00000147655.
DR   UCSC; uc064pmi.1; human.
DR   EuPathDB; HostDB:ENSG00000147655.10; -.
DR   HGNC; HGNC:28583; RSPO2.
DR   OpenTargets; ENSG00000147655; -.
DR   eggNOG; ENOG410IMS2; Eukaryota.
DR   eggNOG; ENOG410ZI6H; LUCA.
DR   GeneTree; ENSGT00940000159194; -.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000147655; Expressed in 100 organ(s), highest expression level in lung.
DR   ExpressionAtlas; E5RGU9; baseline and differential.
DR   InterPro; IPR006212; Furin_repeat.
DR   Pfam; PF15913; Furin-like_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22     76       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008413786.
FT   NON_TER      76     76       {ECO:0000313|Ensembl:ENSP00000430973}.
SQ   SEQUENCE   76 AA;  9026 MW;  72E687FB9D34DB9F CRC64;
     MQFRLFSFAL IILNCMDYSH CQGNRWRRSK RASYVSNPIC KGCLSCSKDN GCSRCQQKLF
     FFLRREGMRQ YGECLH
//