ID   E5RG36_HUMAN            Unreviewed;        82 AA.
AC   E5RG36;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Clusterin {ECO:0000313|Ensembl:ENSP00000427868};
DE   Flags: Fragment;
GN   Name=CLU {ECO:0000313|Ensembl:ENSP00000427868};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000427868, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000427868, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000427868}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000428526}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AF311103; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; E5RG36; -.
DR   MaxQB; E5RG36; -.
DR   PRIDE; E5RG36; -.
DR   Ensembl; ENST00000519472; ENSP00000427868; ENSG00000120885.
DR   Ensembl; ENST00000523396; ENSP00000428526; ENSG00000120885.
DR   UCSC; uc064lmc.1; human.
DR   EuPathDB; HostDB:ENSG00000120885.19; -.
DR   HGNC; HGNC:2095; CLU.
DR   OpenTargets; ENSG00000120885; -.
DR   eggNOG; ENOG410IHRB; Eukaryota.
DR   eggNOG; ENOG410YYKB; LUCA.
DR   GeneTree; ENSGT00530000063668; -.
DR   ChiTaRS; CLU; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000120885; Expressed in 238 organ(s), highest expression level in tendon of biceps brachii.
DR   ExpressionAtlas; E5RG36; baseline and differential.
DR   InterPro; IPR016016; Clusterin.
DR   InterPro; IPR000753; Clusterin-like.
DR   PANTHER; PTHR10970; PTHR10970; 1.
DR   PANTHER; PTHR10970:SF1; PTHR10970:SF1; 1.
DR   Pfam; PF01093; Clusterin; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:E5RG36,
KW   ECO:0000213|MaxQB:E5RG36, ECO:0000213|PeptideAtlas:E5RG36};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23     82       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014570864.
FT   COILED       53     82       {ECO:0000256|SAM:Coils}.
FT   NON_TER      82     82       {ECO:0000313|Ensembl:ENSP00000427868}.
SQ   SEQUENCE   82 AA;  9325 MW;  7E7D13639780A105 CRC64;
     MMKTLLLFVG LLLTWESGQV LGDQTVSDNE LQEMSNQGSK YVNKEIQNAV NGVKQIKTLI
     EKTNEERKTL LSNLEEAKKK KE
//